Results 61 to 70 of about 3,628,620 (342)
Particle accelerators are precious tools, not only for high-energy and nuclear physics, but also for many other areas of science, medicine, and security. They do, however, have a substantial energy consumption, which makes it important to design them to make best use of the consumed energy.
Satyanarayana Chanagala, Z. J. Khan
+4 more sources
Validation of black-box performance models for a water-to-water heat pump operating under steady state and dynamic loads [PDF]
The use of simple mathematical models for describing the behaviour of heat pumps is important for assessing the energy performance of this equipment when installed in buildings.
Fuentes Elena, Salom Jaume
doaj +1 more source
Monitoring of the “Energiewende” – energy efficiency indicators for Germany [PDF]
The increasing number of energy and climate targets both at national and international level induces a rising demand for regular monitoring. In this paper, we analyse the possibilities and limits of using energy efficiency indicators as a tool for ...
Lapillonne, Bruno +4 more
core +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Energy Efficiency Strategy for Big Data in Cloud Environment Using Deep Reinforcement Learning [PDF]
Neeraj Kumar Pandey +5 more
openalex +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Energy conversion and distribution of heat and electricity is characterized by long planning horizons, investment periods and depreciation times, and it is thus difficult to plan and tell the technology that optimally fits for decades.
Jonas Hinker +5 more
doaj +1 more source
Energy efficiency measurement procedure for gearboxes in their entire operating range [PDF]
Over the last decade, forced regulations and a growing social awareness with respect to energy efficiency have resulted in a renewed interest in the research for high efficient electrical machines.
Algoet, Elewijn +5 more
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source

