Results 81 to 90 of about 848,604 (282)

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

To estimation of the Energy Efficiency Design Index (EEDI) for a ship with energy-saving wing devices

MORSKIE INTELLEKTUAL`NYE TEHNOLOGII)</msg>, 2021
В статье приводится оценка индекса проектной энергетической эффективности (EEDI) для судна с энергосберегающими крыльевыми устройствами на встречном регулярном волнении. Вначале на основе предыдущих работ авторов с применением линейной теории поперечных сечений определяются характеристики продольной (вертикальной и килевой) качки судна без крыльев, и ...
openaire   +1 more source

Using muon rings for the optical throughput calibration of the SST-1M prototype for the Cherenkov Telescope Array

, 2015
Imaging Atmospheric Cherenkov Telescopes (IACTs) are ground-based instruments devoted to the study of very high energy gamma-rays coming from space. The detection technique consists of observing images created by the Cherenkov light emitted when gamma ...
Bilnik, W., Bogacz, L., Bulik, T., Błocki, J., Cadoux, F., Christov, A., Curyło, M., della Volpe, D., Dyrda, M., Favre, Y., Frankowski, A., Grudnik, Ł., Grudzińska, M., Heller, M., Idźkowski, B., Jamrozy, M., Janiak, M., Kasperek, J., Lalik, K., Lyard, E., Mach, E., Mandat, D., Marszałek, A., Michałowski, J., Moderski, R., Montaruli, T., Neronov, A., Niemiec, J., Ostrowski, M., Paśko, P., Pech, M., Porcelli, A., Prandini, E., Pujadas, I. Troyano, Rajda, P., Rameez, M., Schioppa, E. jr., Schovanek, P., Seweryn, K., Skowron, K., Sliusar, V., Sowiński, M., Stawarz, Ł., Stodulska, M., Stodulski, M., Toscano, S., Walter, R., Więcek, M., Zagdański, A., Ziętara, K., Żychowski, P.   +50 more
core   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

High-Throughput Signal Component Separator for Asymmetric Multi-Level Outphasing Power [PDF]

—This paper presents an energy-efficient highthroughput and high-precision signal component separator (SCS) chip design for the asymmetric-multilevel-outphasing (AMO) power amplifier.
Oguzhan Uyar, Re Megretski, Vladimir Stojanović, Yan Li, Yehuda Avniel, Zhipeng Li   +5 more
core  

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Dynamic Energy Management for Chip Multi-processors under Performance Constraints [PDF]

, 2017
We introduce a novel algorithm for dynamic energy management (DEM) under performance constraints in chip multi-processors (CMPs). Using the novel concept of delayed instructions count, performance loss estimations are calculated at the end of each ...
Ababei, Cristinel, Moghaddam, Milad Ghorbani   +1 more
core   +1 more source

Sustainable bioplastics manufacturing from renewable sources

FEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto, Marika Avitabile, Michela Famiglietti, Talayeh Kordjazi, Marzieh Moosavi‐Nasab, Odile F. Restaino, Loredana Mariniello   +6 more
wiley   +1 more source

ENERGY EFFICIENCY IN THE SHIPPING SECTOR – A CASE STUDY [PDF]

Analele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2017
The improvement of Ship Energy Efficiency has been a major issue for the Shipping industry, primarily for three reasons; Firstly because fuel expenses of merchant ships contribute substantially to the overall expenses, secondarily, as conventional ...
BRANISLAV DRAGOVIŠ, ERNESTOS TZANNATOS, VASSILIS ΤSELENTIS, AMALIA-VENERA TODORUT   +3 more
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