Results 121 to 130 of about 2,591,056 (296)

The mass and radius evolution of globular clusters in tidal fields

, 2013
We present a simple theory for the evolution of initially compact clusters in a tidal field. The fundamental ingredient of the model is that a cluster conducts a constant fraction of its own energy through the half-mass radius by two-body interactions ...
Gieles, Mark
core  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Mechanisms and influential factors of rock bursts in tunneling roadways of extra-thick coal seams

Meitian dizhi yu kantan
ObjectiveRock bursts occur frequently in tunneling roadways of extra-thick coal seams, significantly constraining safe coal mining. Investigating their mechanisms and influential factors is crucial to preventing and controlling such disasters in ...
Yujie PENG, Qiang WANG, Anye CAO, Chengchun XUE, Guowei LYU, Qi HAO, Yaoqi LIU, Xianxi BAI, Dong LI   +8 more
doaj   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Effect of CO₂ Nanobubble Water on the Fracture Properties of Cemented Backfill Materials under Different Aggregate Fractal Dimensions

Applied Sciences
In order to cope with climate change and achieve the goal of carbon neutrality, the use of carbonization technology to enhance the performance of cement-based materials and achieve the purpose of carbon sequestration has become a very promising research ...
Xiaoxiao Cao, Akihiro Hamanaka, Hideki Shimada, Takashi Sasaoka   +3 more
doaj   +1 more source

Sustainable bioplastics manufacturing from renewable sources

FEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto, Marika Avitabile, Michela Famiglietti, Talayeh Kordjazi, Marzieh Moosavi‐Nasab, Odile F. Restaino, Loredana Mariniello   +6 more
wiley   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Study on Energy Evolution Law of Rocks With Different Lithologies and Sizes

Energy Science & Engineering
Investigating the actual patterns of energy accumulation and release in roof rock, particularly with varying stiffnesses in mining environments, is crucial.
Yanchun Yin, Zitong Gao, Zhigang Zhao, Shudong He, Liyuan Liu, Guoying Li   +5 more
doaj   +1 more source