Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Energy Evolution and Fine Structure Effects in Typical Rocks Subjected to Impact Loading. [PDF]
Deng D, Liu G, Guo L, Li Y, Hua J.
europepmc +1 more source
Adenosine triphosphate as a modulator of protein interactions and stability
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
Failure mechanisms and energy evolution of jointed rock-like materials under triaxial compression: experimental and numerical simulation study. [PDF]
Dou H +5 more
europepmc +1 more source
Failure energy evolution of coal-rock combination with different inclinations. [PDF]
Yu Y +7 more
europepmc +1 more source
Energy Activities With Energy Ant
"This little friend has been created by the Federal Energy Administration to tell kids about energy and how to use it wisely" (p. i)
Federal Energy Administration. Office of Communications and Public Affairs.
core
Heterotropic regulation and negative homotropic cooperativity
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Energy evolution mechanism of hard roof of working face adjacent to goaf after hydraulic fracturing and application. [PDF]
Liu X, Liu H, Dong J, Sun W.
europepmc +1 more source
Study on the energy evolution mechanism of coal and rock with impact tendency under different strain rates. [PDF]
Zhang K +6 more
europepmc +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source

