Results 81 to 90 of about 6,670,403 (347)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Fast design space exploration of vibration-based energy harvesting wireless sensors

, 2013
An energy-harvester-powered wireless sensor node is a complicated system with many design parameters. To investigate the various trade-offs among these parameters, it is desirable to explore the multi-dimensional design space quickly. However, due to the
Al-Hashimi, Bashir, Aloufi, Mansour, Kazmierski, Tom, Merrett, Geoff V., Wang, Leran   +4 more
core   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Study of the Properties of a Hybrid Piezoelectric and Electromagnetic Energy Harvester for a Civil Engineering Low-Frequency Sloshing Environment

Energies, 2021
In this paper a novel hybrid piezoelectric and electromagnetic energy harvester for civil engineering low-frequency sloshing environment is reported. The architecture, fabrication and characterization of the harvester are discussed.
Nan Wu, Yuncheng He, Jiyang Fu, Peng Liao   +3 more
doaj   +1 more source

Energy consumption optimization for thermal energy harvester applications [PDF]

, 2020
This paper demonstrates the concept of node consumption reduction for IoT applications. The main emphasis is placed on the autonomy of the whole device, which must be independent of external power supply.
Bouřa A., Husák M., Janíček V., Novák J., Teplý T.   +4 more
core  

A stacked electromagnetic energy harvester with frequency up-conversion for swing motion

Applied Physics Letters, 2020
This paper undertakes theoretical and experimental investigations of a stacked magnetic modulation harvester with frequency up-conversion for energy harvesting performance enhancement from swing motion.
Ning Zhou, Ying Zhang, C. Bowen, Junyi Cao   +3 more
semanticscholar   +1 more source

Experimental Realization of a Quantum Dot Energy Harvester. [PDF]

Physical Review Letters, 2019
We demonstrate experimentally an autonomous nanoscale energy harvester that utilizes the physics of resonant tunneling quantum dots. Gate-defined quantum dots on GaAs/AlGaAs high-electron-mobility transistors are placed on either side of a hot-electron ...
G. Jaliel, R. Puddy, R. Sánchez, A. Jordan, B. Sothmann, I. Farrer, J. Griffiths, D. A. Ritchie, Charles G. Smith   +8 more
semanticscholar   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Fundamental Limits to Nonlinear Energy Harvesting [PDF]

, 2014
Linear and nonlinear vibration energy harvesting has been the focus of considerable research in recent years. However, fundamental limits on the harvestable energy of a harvester subjected to an arbitrary excitation force and different constraints is not
Haji Hosseinloo, Ashkan, Turitsyn, Konstantin   +1 more
core   +4 more sources

Performance Evaluation of a Piezoelectric Energy Harvester Based on Flag-Flutter

Micromachines, 2020
In the last few decades, piezoelectric (PZT) materials have played a vital role in the aerospace industry because of their energy harvesting capability.
H. Elahi, M. Eugeni, Federico Fune, L. Lampani, F. Mastroddi, Giovanni Paolo Romano, P. Gaudenzi   +6 more
semanticscholar   +1 more source