Results 71 to 80 of about 493,320 (289)

Piezoelectric vibration energy harvester: Operating mode, excitation type and dynamics

open access: yesAdvances in Mechanical Engineering, 2022
Nowadays, with the rapid development of the intelligent era and the concept of Internet of Things being proposed, more and more sensors will play a more important role.
Weipeng Zhou   +6 more
doaj   +1 more source

Soft Capacitors for Wave Energy Harvesting

open access: yes, 2011
Wave energy harvesting could be a substantial renewable energy source without impact on the global climate and ecology, yet practical attempts have struggle d with problems of wear and catastrophic failure.
Abel, Markus   +4 more
core   +1 more source

MEMS vibrational energy harvesters [PDF]

open access: yesScience and Technology of Advanced Materials, 2019
In this paper, we look into the fundamental mechanism to retrieve the power from physical vibrations by using microelectromechanical systems (MEMS) energy harvesters. An analytical model is presented for the velocity-damped resonant generator (VDRG) that delivers electrical power through the power enhancement mechanism using the mechanical resonance of
Hiroshi Toshiyoshi   +4 more
openaire   +3 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Nanomaterials for Energy Harvesting

open access: yesNanomaterials, 2023
Energy harvesting is no longer simply an academic issue; it has grown into a problem with real industrial and even social significance [...]
openaire   +3 more sources

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

High-performance, mini modules (∼1 cm2) of halide perovskite indoor photovoltaics with carbon counter electrode and sensor powering

open access: yesJPhys Energy
Halide perovskite indoor photovoltaics present a promising pathway for sustainably powering the rapidly growing network of wireless sensors in the Internet of Things.
Hugo Decitre   +7 more
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

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