Results 31 to 40 of about 171,998 (254)

Roles of Earth’s Albedo Variations and Top-of-the-Atmosphere Energy Imbalance in Recent Warming: New Insights from Satellite and Surface Observations

Geomatics
Past studies have reported a decreasing planetary albedo and an increasing absorption of solar radiation by Earth since the early 1980s, and especially since 2000. This should have contributed to the observed surface warming.
Ned Nikolov, Karl F. Zeller
doaj   +1 more source

Impact of PV/Wind Forecast Accuracy and National Transmission Grid Reinforcement on the Italian Electric System

Energies, 2022
The high share of PV energy requires greater system flexibility to address the increased demand/supply imbalance induced by the inherent intermittency and variability of the solar resource.
Marco Pierro, Fabio Romano Liolli, Damiano Gentili, Marcello Petitta, Richard Perez, David Moser, Cristina Cornaro   +6 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Nutritional alterations, adverse consequences, and comprehensive assessment in spinal cord injury: a review

Frontiers in Nutrition
Spinal cord injury (SCI) leads to complex nutritional alterations, including energy imbalance, skewed macronutrient and micronutrient intake, and disrupted nutrient absorption and metabolism.
Zehui Li, Zehui Li, Xiaoxin Wang, Xiaoxin Wang, Yan Yu, Yan Yu, Yan Yu, Yingli Jing, Yingli Jing, Yingli Jing, Huayong Du, Huayong Du, Wubo Liu, Wubo Liu, Wubo Liu, Chunjia Zhang, Chunjia Zhang, Chunjia Zhang, Zuliyaer Talifu, Zuliyaer Talifu, Zuliyaer Talifu, Xin Xu, Xin Xu, Xin Xu, Yunzhu Pan, Yunzhu Pan, Yunzhu Pan, Jianjun Li, Jianjun Li, Jianjun Li, Jianjun Li   +30 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Multi‐Omics and ‐Organ Insights into Energy Metabolic Adaptations in Early Sepsis Onset

Advanced Science
Systemic metabolic dysregulation in sepsis critically impacts patient survival. To better understand its onset, untargeted serum metabolomics and lipidomics are analyzed from 152 presymptomatic patients undergoing major elective surgery, and identified ...
Lin‐Lin Xu, Zhengyuan Zhou, Sascha Schäuble, Wolfgang Vivas, Karen Dlubatz, Michael Bauer, Sebastian Weis, Mervyn Singer, Roman Lukaszewski, Gianni Panagiotou   +9 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

An imperative to monitor Earth's energy imbalance [PDF]

Nature Climate Change, 2016
The current Earth's energy imbalance (EEI) is mostly caused by human activity, and is driving global warming. The absolute value of EEI represents the most fundamental metric defining the status of global climate change, and will be more useful than using global surface temperature.
Schuckmann, K., Palmer, M. D., Trenberth, K. E., Cazenave, A., Chambers, D., Champollion, N., Hansen, J., Josey, S. A., Loeb, N., Mathieu, P. -P., Meyssignac, B., Wild, M.   +11 more
openaire   +5 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source