Results 91 to 100 of about 11,750,507 (357)

Vertical separation of the energy-distribution industry; an assessment of several options for unbundling [PDF]

open access: yes
The Dutch Minister of Economic Affairs has proposed to replace the currently implemented structure of legal unbundling of the energy distribution industry by ownership unbundling. In this study we analyse the costs and benefits of this proposal.
Machiel Mulder   +2 more
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Influence of preparation processes on thermophysical properties of molten salt

open access: yesAIP Advances, 2020
Molten salt has been widely studied as a heat storage material, but some properties of molten salt reported in different literature studies are not completely consistent.
Chuang Zhu, Li Gong, Sheng-nian Tie
doaj   +1 more source

Energy Abundance, Trade and Industry Location [PDF]

open access: yes
We study the effect of countries’ energy abundance on trade and sector activity, conditional on sector’s energy intensity, using an unbalanced panel with 14 high-income countries from Europe, America and Asia, 10 broad sectors, and years 1970-1997.
Nicole A. Mathys, Reyer Gerlagh
core  

Industrial Energy Efficiency: Using New Technologies to Reduce Energy Use in Industry and Manufacturing [PDF]

open access: yes, 2006
Key facts: -Industry uses over one-third of the energy consumed in the United States.- Oil and natural gas provide nearly four-fifths of industrial energy; the rest comes mostly from electricity and coal. - Between 1990 and 2003, US industrial output has

core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Stratospheric influence on ECMWF sub‐seasonal forecast skill for energy‐industry‐relevant surface weather in European countries

open access: yesQuarterly Journal of the Royal Meteorological Society, 2020
Meteorologists in the energy industry increasingly draw upon the potential for enhanced sub‐seasonal predictability of European surface weather following anomalous states of the winter stratospheric polar vortex (SPV).
Dominik Büeler   +3 more
semanticscholar   +1 more source

Wind Energy Resource Base and Incentives [PDF]

open access: yes, 2006
Key facts: - At the beginning of 2006, the U.S. wind industry has a total generating capacity of 9,149 MW. - In 2005, the U.S. wind energy industry installing nearly 2,500 megawatts (MW) or over $3 billion worth of new generating equipment in 22 states ...

core  

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

open access: yesFEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl   +13 more
wiley   +1 more source

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