Results 51 to 60 of about 170,371 (265)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Renewable Energy Finance Tracking Initiative (REFTI) Solar Trend Analysis [PDF]

open access: yes, 2012
This report is a summary of the finance trends for small-scale solar photovoltaic (PV) projects (PV
Lowder, T.   +3 more
core   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Large Hospital 50% Energy Savings: Technical Support Document [PDF]

open access: yes, 2010
This Technical Support Document documents the technical analysis and design guidance for large hospitals to achieve whole-building energy savings of at least 50% over ANSI/ASHRAE/IESNA Standard 90.1-2004 and represents a step toward determining how to ...
Bonnema, E.   +9 more
core   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Sustainability of Output Growth in Indian Manufacturing: A Decomposition Analysis of Selected Industries [PDF]

open access: yes
The present paper undertakes a decomposition analysis of the output growth of Indian manufacturing sector. Such an exercise becomes important in view of the non-sustainability of growth proposed by Krugman for the East Asian countries.
Kaustuva Barik, Gopinath Pradhan
core  

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Energy analysis of India's nuclear power programme

open access: yes, 2019
The objective of this paper is to examine the energy profitability of India's nuclear power programme on installing 10.000MW of generating capacity by the year 2000.
Henham, Alex, Prakash, Ravi
core   +1 more source

Allocation of energy inputs among the end-uses in the US petroleum and coal products industry

open access: yes, 2007
This paper models the allocation of energy inputs in the US petroleum and coal products industry by allocating combustible fuel and renewable energy inputs among generic end-uses, including intermediate conversions through onsite power and steam ...
Hyman, Barry, Ozalp, Nesrin
core   +1 more source

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source

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