Results 51 to 60 of about 783,241 (303)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The effects of fair allocation principles on energy system model designs

open access: yesEnvironmental Research: Energy
What constitutes socially just or unjust energy systems or transitions can be derived from philosophy and theories of justice. Assessments of distributive justice and utilising them in modelling lead to great differences based on which justice principles
Oskar Vågerö   +2 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Inequality and sustainable consumption: Bridging the gaps [PDF]

open access: yes, 2008
This article examines the potential for cross-fertilisation between the sustainable consumption (SC) scholarship and the environmental justice (EJ) scholarship.
Paavola, J, Seyfang, G
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Renewable Energy Justice in Rural Indonesia: Legal Strategies for Sustainable and Resilient Development [PDF]

open access: yesE3S Web of Conferences
As Indonesia transitions toward cleaner energy sources, achieving sustainable development in rural regions remains difficult due to persistent legal, infrastructural, and equity challenges.
Arumbinang Mohammad Hazyar   +1 more
doaj   +1 more source

Logic of gauge [PDF]

open access: yes, 2017
The logic of gauge theory is considered by tracing its development from general relativity to Yang-Mills theory, through Weyl's two gauge theories. A handful of elements---which for want of better terms can be called \emph{geometrical justice}, \emph ...
Afriat, Alexander
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

The organizational ecosystem change model for sustainability and justice

open access: yesFrontiers in Sustainability
Addressing complex societal challenges like sustainability and justice requires significant coordinated action within and across organizations. But existing theories for understanding organizational change generally focus on change within a single ...
Mokshda Kaul   +4 more
doaj   +1 more source

Climate justice and energy : applying international principles to UK residential energy policy [PDF]

open access: yes, 2017
There are ethical, legal and strategic/pragmatic reasons why it is important to ensure a just approach to climate change mitigation, both internationally and within nations.
Fawcett, Tina   +2 more
core   +1 more source

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