Results 21 to 30 of about 330,235 (253)
PENGELOLAAN ENERGI (Energy Management)
, 2023 Buku Manajemen Energi merupakan buku yang berisi pengajaran matakuliah manajemen energi dan khususnya manajemen energi listrik. Penyajian buku ini disederhanakan sedemikian rupa sehingga para mahasiswa dan pembaca lainnya akan mudah mengerti setiap pembahasan materi yang disajikan.
openaire +1 more source
Improving Energy Efficiency in Buildings
, 2014 About one-third of global energy is consumed in residential, public, and commercial buildings (collectively referred to as buildings), where it is used for space heating, cooling, ventilating, lighting, cooking,
Energy Sector Management Assistance Program
core +1 more source
Financing Municipal Energy Efficiency Projects
, 2014 Improving the energy efficiency (EE) of municipally owned buildings, such as schools and hospitals, and municipal infrastructure, such as public lighting, water supply, and district heating, offers budgetary savings
Energy Sector Management Assistance Program
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
First Regional Super ESPC: Success on Kodiak Island, Alaska [PDF]
, 2001 This case study about energy saving performance contacts (ESPCs) presents an overview of how the Coast Guard at Kodiak Island, Alaska, established an ESPC contract and the benefits derived from it.
Federal Energy Management Program
core
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Communications and Collaboration Keep San Francisco VA Medical Center Project on Track [PDF]
, 2001 This case study about energy saving performance contacts (ESPCs) presents an overview of how the Veterans Affairs Medical Center in San Francisco established an ESPC contract and the benefits derived from it.
Federal Energy Management Program
core
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source