Results 51 to 60 of about 3,310,482 (285)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

How Smart Metering and Smart Charging may Help a Local Energy Community in Collective Self-Consumption in Presence of Electric Vehicles

Energies, 2020
The 2018/2001/EU renewable energy directive (RED II) underlined the strategic role of energy communities in the EU transition process towards sustainable and renewable energy.
Giuseppe Barone, Giovanni Brusco, Daniele Menniti, Anna Pinnarelli, Gaetano Polizzi, Nicola Sorrentino, Pasquale Vizza, Alessandro Burgio   +7 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Evaluation of Building Energy Savings Achievable with an Attached Bioclimatic Greenhouse: Parametric Analysis and Solar Gain Control Techniques

Buildings, 2022
Bioclimatic solar greenhouses are passive solar systems of relevant interest in the building sector, as they allow the reduction of energy needs related to air-conditioning.
Dimitrios Kaliakatsos, Francesco Nicoletti, Francesca Paradisi, Piero Bevilacqua, Natale Arcuri   +4 more
doaj   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Application of the transdisciplinary shipyard energy management framework by employing a fuzzy multiple attribute group decision making technique toward a sustainable shipyard: case study for a Bangladeshi shipyard

Journal of Shipping and Trade, 2022
Shipbuilding is an energy-intensive industrial sector that produces a significant amount of waste, pollution and air emissions. However, the International Maritime Organization concentrates only on reducing emissions during the operational phase.
Seyedvahid Vakili, Alessandro Schönborn, Aykut I. Ölçer   +2 more
doaj   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Optimizing sustainable solar panel recycling: A feasibility study of mechanical recycling method [PDF]

E3S Web of Conferences
This paper proposes a cost estimation model for a mechanical solar panel recycling plant with multiple integrated processes. A sensitivity analysis evaluates various plant capacity scenarios, assumed by the expected market share percentage within the ...
Sukaviriya Sarakorn, Ratanakuakangwan Sudlop   +1 more
doaj   +1 more source

Energy Efficient Handover Management in Cluster Based Wireless Sensor Network [PDF]

, 2014
Wireless sensors are compact-size, low power, inexpensive devices which are capable to measure local environmental conditions or other parameters such as temperature, acceleration, and forward such information to a sink for proper processing.
Alghamdi, M. I. (Muhammed), Baharun, S. (Sabariah), Budiarto, R. (Rahmat), Islam, A. K. (A), Zareei, M. (Mahdi)   +4 more
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Energy use for urban water management by utilities and Households in Los Angeles [PDF]

, 2020
Reducing energy consumption for urban water management may yield economic and environmental benefits. Few studies provide comprehensive assessments of energy needs for urban water sectors that include both utility operations and household use.
Escriva-Bou, A, Federico, F, Fournier, ED, Gold, M, Mika, KB, Pincetl, S, Porse, E, Sanders, KT, Spang, E, Stokes-Draut, J   +9 more
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