Results 121 to 130 of about 19,320,857 (380)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Catalytic study of efficient nanocomposites {Ni0.5 Zn0.5−x Cex -oxides electrodes} for natural gas-fed fuel cells

Materials Research Express, 2020
Highly catalytic active anode materials are one of the scorching zones in recent solid oxide fuel cells (SOFCs). In order to develop high performance SOFCs compatible anode materials are extremely required.
Zuhra Tayyab, Saif Ur Rehman, Imran Shakir, M Ajmal Khan, Naveed Mushtaq, Farah Alvi, Sajid Rauf, Aqsa Khan, Mahin Fatima, Rizwan Raza   +9 more
doaj   +1 more source

Self-Similar Law of Energy Release before Materials Fracture

, 2004
A general law of energy release is derived for stressed heterogeneous materials, being valid from the starting moment of loading till the moment of materials fracture.
A. Moura, Anifrani, Bernasconi, Borodich, Borodich, Borodich, Borodich, Broberg, Dietrich, H. Nechad, Herrmann, Johansen, Kachanov, Lamagnère, Moura, Nauenberg, Sahimi, Sornette, Sornette, V.I. Yukalov, Yukalov, Yukalov, Yukalov, Yukalov, Yukalov, Yukalov, Yukalov, Yukalov, Yukalov, Yukalov, Yukalov, Yukalov   +31 more
core   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

The effects of k-dependent self-energy in the electronic structure of correlated materials

, 2012
It is known from self-energy calculations in the electron gas and sp materials based on the GW approximation that a typical quasiparticle renormalization factor (Z factor) is approximately 0.7-0.8.
Aryasetiawan, Ferdi,, Lund University., Martins, C., Miyake, T., Sakuma, Rei,   +4 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Vibrational Energy Transfer from Photo-Excited Carbon Nanotubes to Proteins Observed by Coherent Phonon Spectroscopy

, 2017
Vibrational energy transfer from photo-excited single-wall carbon nanotubes (SWCNTs) to coupled proteins is a key to engineer thermally induced biological reactions such as photothermal therapy.
Hase, Muneaki, Hirano, Atsushi, Nakayama, Tomohito, Shiraki, Kentaro, Tanaka, Takeshi, Yoshizawa, Shunsuke   +5 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Unique activity of a Keggin POM for efficient heterogeneous electrocatalytic OER

iScience
Summary: Polyoxometalates (POMs) have been well studied and explored in electro/photochemical water oxidation catalysis for over a decade. The high solubility of POMs in water has limited its use in homogeneous conditions. Over the last decade, different
Chandani Singh, Dan Meyerstein, Zorik Shamish, Dror Shamir, Ariela Burg   +4 more
doaj   +1 more source

On the rules of life and Kleiber's law: the macroscopic relationship between materials and energy

, 2022
Benjamín Leiva, John R. Schramski
openalex   +1 more source