Results 111 to 120 of about 8,934,147 (357)

Scaling Behaviors of Weighted Food Webs as Energy Transportation Networks

, 2010
Food webs can be regarded as energy transporting networks in which the weight of each edge denotes the energy flux between two species. By investigating 21 empirical weighted food webs as energy flow networks, we found several ubiquitous scaling ...
Albert, Allesina, Almaas, Baird, Banavar, Barber, Barrat, Berlow, Brown, Chen, Clementi, Cohen, Duan, Dunne, Emmerson, Fath, Fath, Finn, Garlaschelli, Goldstein, Hannon, Hannon, Herrada, Higashi, Higashi, Jiang Zhang, Kleiber, Leontief, Leontief, Levine, Liangpeng Guo, McCann, Montis, Montoya, Newman, Noether, Odum, Patten, Patten, Patten, Rousseau, Szyrmer, Ulanowicz, Ulanowicz, Ulanowicz, Ulanowicz, Waldrop, Watts, West, Williams, Wootton   +50 more
core   +1 more source

LKB1 is essential for the proliferation of T-cell progenitors and mature peripheral T cells [PDF]

, 2010
The serine/threonine kinase LKB1 has a conserved role in Drosophila and nematodes to co-ordinate cell metabolism. During T lymphocyte development in the thymus, progenitors need to synchronize increased metabolism with the onset of proliferation and ...
Aifantis, Aifantis, Alessi, Azzam, Bonaccorsi, Borowski, Boudeau, Bozulic, Cantrell, Cantrell, Cantrell, Chang, Choi, Ciofani, Ciofani, de Pooter, Frauwirth, Goldstein, Hardie, Hardie, Hayday, Hemminki, Hezel, Hinton, Hurov, Hurov, Ji, Jones, Juntilla, Kelly, Koo, Laky, Lee, Liang, Lizcano, Mao, Mayer, Michie, Mirouse, Partanen, Rodewald, Sakamoto, Sanchez-Cespedes, Schmitt, Shaw, Shaw, Smith-Garvin, Takahama, Takahama, Tamas, Ylikorkala   +50 more
core   +5 more sources

Energy metabolism in ALS: an underappreciated opportunity?

Acta Neuropathologica, 2018
Amyotrophic lateral sclerosis (ALS) is a relentlessly progressive and fatal neurodegenerative disorder that primarily affects motor neurons. Despite our increased understanding of the genetic factors contributing to ALS, no effective treatment is ...
T. Vandoorne, Katrien de Bock, L. Van Den Bosch   +2 more
semanticscholar   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Can urban metabolism models advance green infrastructure planning? Insights from ecosystem services research [PDF]

, 2018
Urban metabolism studies have gained momentum in recent years as a means to assess the environmental performance of cities and to point to more resource-efficient strategies for urban development.
Perrotti, Daniela, Stemke, Sven
core   +1 more source

Adipose Tissue Remodeling: Its Role in Energy Metabolism and Metabolic Disorders

Frontiers in Endocrinology, 2016
The adipose tissue is a central metabolic organ in the regulation of whole-body energy homeostasis. The white adipose tissue functions as a key energy reservoir for other organs, whereas the brown adipose tissue accumulates lipids for cold-induced ...
S. S. Choe, J. Huh, Injae Hwang, Jong In Kim, Jae Bum Kim   +4 more
semanticscholar   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

Molecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla, Simone Venz, Ruslan Al‐Ali, Martin Wendlandt, Mandy Radefeldt, Elke Krüger   +5 more
wiley   +1 more source

Chronic acceleration studies - Physiological responses to artificial alterations in weight Progress report [PDF]

Influence of chronic acceleration on energy metabolism of chickens and animals, as indicated by maintenance feed ...
Besch, E. L., Burton, R. R., Kelly, C. F., Sluka, S. J., Smith, A. H.   +4 more
core   +1 more source

Genetic sensitivity to the bitter taste of 6-n-propylthiouracil (PROP) and its association with Physiological mechanisms controlling Body Mass Index (BMI) [PDF]

, 2014
Taste sensitivity to the bitter compound 6-n-propylthiouracil (PROP) is considered a marker for individual differences in taste perception that may influence food preferences and eating behavior, and thereby energy metabolism.
Banni S, Crnjar R, Melis M, Tepper BJ, Tomassini Barbarossa I   +4 more
core   +1 more source