Results 51 to 60 of about 18,261,083 (260)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Promotion of Efficient Use of Energy: Final Report
, 2006 The Department of Energy funded the Alliance to Save Energy to promote the efficient use of energy under a multiyear cooperative agreement. This funding allowed the Alliance to be innovative and flexible in its program development, and to initiate and ...
Alliance to Save Energy (U.S.)
core +1 more source
IDENTIFICATION METHOD FOR PENDULUM SYSTEM MOMENT OF INERTIA WITH VISCOUS DAMPING [PDF]
Научно-технический вестник информационных технологий, механики и оптики, 2016 The paper proposes a method for identification of axial moment of inertia of the mechanical system called reaction wheel pendulum with a viscous friction in the bearings of the suspension. The method is based on the reversible symmetric motions. Pendulum
A. S. Alyshev +2 more
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
A Blueprint for Ocean Energy Development 2010-2015 [PDF]
In an effort to foster a collaborative approach to advancing the ocean energy industry, OWET convened the OWET 2010 Developersʼ Summit on September 27 and 28, 2010 in Portland, Oregon.
Oregon Wave Energy Trust
core +3 more sources
Japan Architectural ReviewThe objective of this study was to analyze the elastic critical local buckling of cold‐formed lipped channel sections using the energy method. A mechanical model and unique displacement functions simulating the local buckling behavior were proposed to ...
Kazuya Mitsui, Kikuo Ikarashi
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
BuildingsThe current constitutive model and damage evolution law of crumb rubber concrete (CRC) were obtained by fitting and changing parameters based on the normal concrete model.
Tongge Guo, Gang Xue, Bolun Fu
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source