Results 121 to 130 of about 22,333,622 (267)

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Carefree Pattern

, 1975
McCall's Carefree Pattern #4387 by Halston to make stretch knit cape with asymmetrical drape and flared skirt with waistband, including illustrations of the finished pieces and information about sizing and construction on the ...
Halston, 1932-1990, McCall's Pattern Company   +1 more
core  

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Comparative Analysis of Estimated Small Wind Energy Using Different Probability Distributions in a Desert City in Northwestern México

Energies
In this paper, four probability functions are compared with the purpose of establishing a methodology to improve the accuracy of wind energy estimations in a desert city in Northwestern Mexico.
Juan A. Burgos-Peñaloza, Alejandro A. Lambert-Arista, O. Rafael García-Cueto, Néstor Santillán-Soto, Edgar Valenzuela, David E. Flores-Jiménez   +5 more
doaj   +1 more source

PATTERN FORMATION PHENOMENA IN CONTACT ROTATING SYSTEMS (SIMPLIFIED METHOD FOR STABILITY ANALYSIS AND PREVENTION MEASURE BY USING ENERGY FACTOR)

The Proceedings of the International Conference on Motion and Vibration Control, 2002
Sowa, Nobuyuki, Kondou, Takahiro
openaire   +1 more source

Patterns of energy intake in patients with cirrhosis and healthy volunteers [PDF]

, 1999
Fuel utilization and N economy are optimized in patients with cirrhosis by provision of several small meals throughout the day and a late-night snack of complex carbohydrate.
Morgan, MY, Madden, AM
core  

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

A New Energy Pattern Factor Method to Estimate Weibull Shape Parameter for Impact Resistance of Concrete

International Journal of Mechanical and Production Engineering Research and Development, 2020
openaire   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source