Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Comparative emission and energy performance of biochar production versus in-situ burning of Gorean agrobyproducts. [PDF]
Park S +7 more
europepmc +1 more source
Mind the Energy Performance Gap: testing the accuracy of building Energy Performance Certificates in Ireland. [PDF]
Coyne B, Denny E.
europepmc +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
Photocatalytic Hydrogen Production Driven by Solar Energy: Performance Under Central European Climatic Conditions. [PDF]
Kluba W +2 more
europepmc +1 more source
Zone-wise occupancy schedules developed using Time Use Survey data for building energy performance simulations. [PDF]
Sood D +6 more
europepmc +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Energy performance of MRI systems: on-site validation and comparison with manufacturer declarations. [PDF]
Roletto A +4 more
europepmc +1 more source
Innovative Passive and Environmentally Friendly System for Improving the Energy Performance of Buildings. [PDF]
Burlacu A +6 more
europepmc +1 more source
Effect of terahertz irradiation on DNA damage repair in living cells
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno +3 more
wiley +1 more source

