Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
District heating in the UK:A Technological Innovation Systems analysis [PDF]
, 2012 District heating infrastructure could contribute to the UK's energy policy goals of decarbonisation, renewable energy deployment, tackling fuel poverty and ensuring energy security.
Hawkey, David
core +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Energy Poverty, Climate Change and Economic Growth [PDF]
, 2021 A. J., Ifarajimi G.D.
openalex +1 more source
Energy poverty indicators : conceptual issues part I: the ten-percent-rule and double median/mean indicators [PDF]
, 2014 Energy poverty, long considered a problem limited to developing countries only, is now widely acknowledged as a challenge for advanced OECD countries as well.
Schuessler, Rudolf
core +2 more sources
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
Mitigating energy poverty: Potential contributions of combining PV and building thermal mass storage in low-income households [PDF]
, 2018 The issue of energy poverty has devastating implications for the society, and it has been aggravated in the past years due to the economic crisis and the increase of energy prices.
Guerrero Delgado, María del Carmen +4 more
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Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Energy poverty in rural and urban India : are the energy poor also income poor ? [PDF]
Energy poverty is a frequently used term among energy specialists, but unfortunately the concept is rather loosely defined. Several existing approaches measure energy poverty by defining an energy poverty line as the minimum quantity of physical energy ...
Barnes, Douglas F. +2 more
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Public's Priorities for 2010: Economy, Jobs, Terrorism [PDF]
, 2010 Presents January 2010 survey findings on the public's top concerns, including trends in views on energy policy and the federal budget deficit and partisan gaps on issues of global warming, poverty, education, the military, and special ...
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