Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Mercury Lα1 High Energy Resolution Fluorescence Detected X-ray Absorption Spectroscopy: A Versatile Speciation Probe for Mercury. [PDF]
Inorg Chem, 2022 Nehzati S +9 more
europepmc +1 more source
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
A new μ-high energy resolution fluorescence detection microprobe imaging spectrometer at the Stanford Synchrotron Radiation Lightsource beamline 6-2. [PDF]
Rev Sci Instrum, 2022 Edwards NP +6 more
europepmc +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers +19 more
wiley +1 more source
Momentum and energy resolution
Methods in MicroscopyThe energy and momentum transfered in an elastic scattering event from a fast electron to a plasmon are intimately linked. The in-plane (q 2D ) and out-of-plane transfered momenta (q z) are however fundamentally distinct in a two dimensional sheet. Their
Kramberger Christian +4 more
doaj +1 more source
Regional Super ESPC Saves Energy and Dollars at NASA's Johnson Space Center
, 2001 This case study about energy saving performance contacts (ESPCs) presents an overview of how the NASA's Johnson Space Flight Center established an ESPC contract and the benefits derived from it.
Program, Federal Energy Management
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Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif +17 more
wiley +1 more source
Impact of selenium addition to the cadmium-zinc-telluride matrix for producing high energy resolution X-and gamma-ray detectors. [PDF]
Sci Rep, 2021 Roy UN +4 more
europepmc +1 more source
Energy Activities With Energy Ant
, 1975 "This little friend has been created by the Federal Energy Administration to tell kids about energy and how to use it wisely" (p. i)
Federal Energy Administration. Office of Communications and Public Affairs.
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