Results 71 to 80 of about 2,653,570 (338)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Energy calibration and performance testing of LEGe detector

The Journal of Engineering, 2019
The low energy germanium detector (LEGe) is in all aspects optimised for performance at low and moderate energies. It has specific advantages over conventional planar or coaxial detectors.
Dongjie Hou, Chong Wu, Chengze Li, Siming Guo, Jinjie Wu   +4 more
doaj   +1 more source

Dynamical characteristics of Rydberg electrons released by a weak electric field

, 2015
The dynamics of ultra-slow electrons in the combined potential of an ionic core and a static electric field is discussed. With state-of-the-art detection it is possible to create such electrons through strong intense-field photo-absorption and to detect ...
Diesen, Elias, Dörner, Reinhard, Kunitski, Maksim, Richter, Martin, Rost, Jan M., Saalmann, Ulf   +5 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

DOI-PET Imaging Investigation Based on 3-D Cross-Strip Cadmium Zinc Telluride Detector

Journal of Isotopes, 2022
To study the PET imaging performance of cross-strip cadmium zinc telluride detector with a size of 16.4 mm×16.4 mm×5 mm, which can determine the 3-D position information of 511 keV gamma photons.
LI Yingguo;CUI Zhencun;GUO Dian;LIU Meilou;WEN Jing;ZHANG Qinghua;PEI Changxu;HUANG Chuan;YIN Yongzhi;LI Gongping
doaj  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Position-sensitive detection of ultracold neutrons with an imaging camera and its implications to spectroscopy

, 2016
Position-sensitive detection of ultracold neutrons (UCNs) is demonstrated using an imaging charge-coupled device (CCD) camera. A spatial resolution less than 15 $\mu$m has been achieved, which is equivalent to an UCN energy resolution below 2 pico ...
Adamek, E. R., Broussard, L. J., Callahan, N. B., Clayton, S. M., Cude-Woods, C., Currie, S., Dees, E. B., Ding, X., Geltenbort, P., Hickerson, K. P., Hoffbauer, M. A., Holley, A. T., Ito, T. M., Leung, K. K., Liu, C. -Y., Makela, M., Morley, D. J., Morris, C. L., Ortiz, Jose D., Pattie, Jr., R. W., Ramsey, J. C., Saunders, A., Seestrom, S. J., Sharapov, E. I., Sjue, S. K., Tang, Z., Wang, Zhehui, Wei, Wanchun, Wexler, J., Womack, T. L., Young, A. R., Zeck, B. A.   +31 more
core   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Energy-resolution Study of Frisch-grid Ionization Chamber Using Multi-wire Proportional Chamber Readout

Yuanzineng kexue jishu
A Frisch-grid ionization chamber detector based on multi-wire proportional chamber readout is built. It is equipped with avalanche amplification while retaining the shielding characteristics of the Frisch-grid ionization chamber to pre-amplify the ...
YIN Xiaohao1,2, WEI Xianglun1, HUANG Xinjie1,2, ZOU Haichuan2,3, QIU Tianli1,2, HE Zhoubo1,2, YANG Yuansheng1,2, LI Zhijie1,2, LI Meng1,2, MA Peng1, YANG Herun1, LU Chengui1, HU Rongjiang1, DUAN Limin1
doaj   +1 more source

Characterization of some modern scintillators recommended for use on large fusion facilities in γ-ray spectroscopy and tomographic measurements of γ-emission profiles

Nukleonika, 2017
LaBr3:Ce,CeBr3 and GAGG:Ce scintillators were investigated and the determined characteristics were compared with those obtained for the well-known and widely used CsI:Tl and NaI:Tl crystals. All the detectors were of the same size of 10 × 10 × 5 mm3. The
Sibczynski Pawel, Broslawski Andrzej, Gojska Aneta, Kiptily Vasili, Korolczuk Stefan, Kwiatkowski Roch, Mianowski Slawomir, Moszyński Marek, Rzadkiewicz Jacek, Swiderski Lukasz, Szydlowski Adam, Zychor Izabella   +11 more
doaj   +1 more source