Results 31 to 40 of about 909,586 (306)
Organic farming and resource efficiency [PDF]
The Chapter discusses the efficiency of nutrient and energy use in organic farming, regarding the pressing need to make efficient use of natural resources.
de Neergaard, Andreas, Oelofse, Myles
core
This trifold describes DOE's Industrial Technologies Program's Save Energy Now campaign, and gives information on partnership opportunities for industry.
openaire +5 more sources
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Energy Saving Potential of Idle Pacman Supercomputing Nodes [PDF]
To determine the energy saving potential of suspending idle supercomputing nodes without sacrificing efficiency, my research involved the setup of a compute node power usage monitoring system.
Lower, Brahm
core
Energy Saving. Energy Saving by Modyfying Turbo-Blower Transmission.
当工場において省エネルギー活動は逐次実施しているが, 今回, 抄紙機において大電力を消費しているターボブロワについて省エネルギーを検討することにした。抄紙機におけるターボブロワは, その吸い込み圧力により濃度の低い原料から水分を搾り取ることや, 水分の多い紙匹をフェルトに接着させ, ロールからロールへと運ぶ目的で使用されている。しかしながら, 近年の新聞用紙の軽量化や, プレスパートにおいて, フェルトシャワーを使用しないドライランニングへと操業方法が変わってきたこと, 又, 抄紙機メーカから提示されるターボブロワ能力は大きめで, 風量, 吸い込み圧力とも余力が大きいこと等から, 実際の操業では手動弁をかなり閉め, 吸い込み圧力を下げた操業をしていた。そこで ...
openaire +2 more sources
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Energy Saving Techniques for Phase Change Memory (PCM) [PDF]
In recent years, the energy consumption of computing systems has increased and a large fraction of this energy is consumed in main memory. Towards this, researchers have proposed use of non-volatile memory, such as phase change memory (PCM), which has ...
Mittal, Sparsh
core
Hot water use in households, for showers and baths as well as for washing clothes and dishes, is a major driver of household energy consumption. Other household uses of water (such as irrigating landscaping) require additional energy in other sectors to transport and treat the water before use, and to treat wastewater.
McMahon, James E. +2 more
openaire +1 more source

