Results 61 to 70 of about 893,191 (304)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Energy Saving Potential of Idle Pacman Supercomputing Nodes [PDF]
, 2012 To determine the energy saving potential of suspending idle supercomputing nodes without sacrificing efficiency, my research involved the setup of a compute node power usage monitoring system.
Lower, Brahm
core
Only reasoned action? An interorganizational study of energy-saving behaviors in office buildings [PDF]
, 2014 Substantial energy savings can be achieved by reducing energy use in office buildings. The reported study used a Theory of Planned Behavior (TPB) model extended with perceived habit to explain office energy-saving behaviors.
Kok, G +3 more
core +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Optimal layout of pressure monitoring points in water supply network based on Optics
E3S Web of Conferences, 2019 It is necessary to monitor the pressure in the networks in real time, when we face the problem of pipe burst and leakage in urban water supply network. Therefore, it is particularly important to arrange pressure monitoring points in appropriate places in
Xie ChenLei +3 more
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
, 2006 This trifold describes DOE's Industrial Technologies Program's Save Energy Now campaign, and gives information on partnership opportunities for industry.
openaire +5 more sources
Energy Saving Techniques for Phase Change Memory (PCM) [PDF]
, 2013 In recent years, the energy consumption of computing systems has increased and a large fraction of this energy is consumed in main memory. Towards this, researchers have proposed use of non-volatile memory, such as phase change memory (PCM), which has ...
Mittal, Sparsh
core
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Journal of Traffic and Transportation Engineering (English ed. Online)As a kind of renewable and high oxygen content fuel, polyoxymethylene dimethyl ether (PODE) can be added in diesel to realize energy saving and emissions reduction.
Xin Su +6 more
doaj +1 more source