Results 41 to 50 of about 108,549 (318)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

The role of built environment energy efficiency in a sustainable UK energy economy

, 2008
Energy efficiency in the built environment can make significant contributions to a sustainable energy economy. In order to achieve this, greater public awareness of the importance of energy efficiency is required.
Clarke, Joseph Andrew, Strachan, P. A., Strachan, Paul, Tuohy, Paul Gerard, Johnstone, C. M., Tuohy, P., Kelly, Nicolas, Johnstone, Cameron, Kelly, N. J., Clarke, J. A.   +9 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Uniform Methods Project: Methods for Determining Energy Efficiency Savings for Specific Measures; January 2012 - March 2013 [PDF]

, 2013
Under the Uniform Methods Project, DOE is developing a framework and a set of protocols for determining the energy savings from specific energy efficiency measures and programs.
Haeri, H., Jayaweera, T.
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Building America Residential System Research Results: Achieving 30% Whole House Energy Savings Level in Marine Climates; January 2006 - December 2006

, 2006
The Building America program conducts the system research required to reduce risks associated with the design and construction of homes that use an average of 30% to 90% less total energy for all residential energy uses than the Building America Research
Consortium for Advanced Residential Buildings, Building Science Consortium, Building America Industrialized Housing Partnership, Building Industry Research Alliance, National Association of Home Builders Research Center, Davis Energy Group, National Renewable Energy Laboratory, IBACOS   +7 more
core   +1 more source

Grocery Store 50% Energy Savings Technical Support Document [PDF]

, 2009
This report documents technical analysis for grocery stores aimed at providing design guidance that achieves whole-building energy savings of at least 50% over ASHRAE Standard 90.1 ...
Hirsch, A., Leach, M., Torcellini, P., Hale, E.   +3 more
core   +1 more source

SAVING ENERGY: A REVIEW ON ENERGY SAVINGS IN LIGHTING BUILDINGS IN AN INSTALLATION

International Journal of Research -GRANTHAALAYAH, 2017
The fossil fuel reserves in India are rapidly exhausting with the country's development. To cope with the energy crisis, end-user efficiency plays an important role. This paper deals with energy saving in lighting systems with the replacement of lighting programs, as in India there is in all sectors a growing demand for energy.
openaire   +3 more sources

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Outer Building Surface Profile as an Effective Parameter in Optimizing Building Energy Efficiency in Egypt’s Climatic Regions [PDF]

Fayoum University Journal of Engineering
Building envelope plays a crucial role in buildings energy efficiency. This study examines the influence of the outer building surface’s self-shading features, such as surface roughness and grooves, along with solar absorptance, on building energy ...
Mai Karram, Hebah Hatem
doaj   +1 more source