Results 71 to 80 of about 687,836 (310)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Energy Saving. Energy Saving by Modyfying Turbo-Blower Transmission.
JAPAN TAPPI JOURNAL, 1996 当工場において省エネルギー活動は逐次実施しているが, 今回, 抄紙機において大電力を消費しているターボブロワについて省エネルギーを検討することにした。抄紙機におけるターボブロワは, その吸い込み圧力により濃度の低い原料から水分を搾り取ることや, 水分の多い紙匹をフェルトに接着させ, ロールからロールへと運ぶ目的で使用されている。しかしながら, 近年の新聞用紙の軽量化や, プレスパートにおいて, フェルトシャワーを使用しないドライランニングへと操業方法が変わってきたこと, 又, 抄紙機メーカから提示されるターボブロワ能力は大きめで, 風量, 吸い込み圧力とも余力が大きいこと等から, 実際の操業では手動弁をかなり閉め, 吸い込み圧力を下げた操業をしていた。そこで ...
openaire +2 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Easy Ways to Lower your Utility Bills [PDF]
, 2008 The average home in Buffalo can expect energy bills of $2,267 per year. An energy-efficient home in Buffalo will have much lower bills – only $1,451 per year. That is a savings of $816.
core +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
EnergiesEnergy Communities (ECs) have emerged as a key instrument for promoting local renewable energy integration and citizen participation in the energy transition.
David González-Asenjo +1 more
doaj +1 more source
Quantifying HVAC Energy Savings Through Occupant-Centric Control: A Computational Simulation Approach [PDF]
JES: Journal of Engineering SciencesSmart systems are a modern technology that positively affects building energy consumption and can significantly reduce the energy cost, especially for office buildings.
Ahmed Elfayoumy
doaj +1 more source
, 2006 Hot water use in households, for showers and baths as well as for washing clothes and dishes, is a major driver of household energy consumption. Other household uses of water (such as irrigating landscaping) require additional energy in other sectors to transport and treat the water before use, and to treat wastewater.
McMahon, James E. +2 more
openaire +1 more source
An Efficient Energy Savings Schemes using Adjacent Lossless Entropy Compression for WSN [PDF]
, 2017 The proposed work aims at designing routing method and data compression algorithm for WSN's. An ad-hoc network (WANET) is considered and based on certain criteria the data is forwarded dynamically.
Baby, C. (Cisil), Suresh, D. H. (Dr)
core +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source