Results 51 to 60 of about 161,293 (301)

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Towards Energy Self-Sufficiency in the Pulp and Paper Industry [PDF]

open access: yes, 1980
The pulp and paper industry is among the most energy intensive in basic industry branches. Rapid price increases for purchased energy and potential risks in its availability during the 1970's have started an intensive and worldwide search for energy ...
Uronen, P.
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Sind mehr Solarmodule immer besser?: Bewertung des kommunalen Kohlenstoffausstoßes

open access: yesTATuP – Zeitschrift für Technikfolgenabschätzung in Theorie und Praxis, 2022
Are more solar panels always better in terms of carbon impact for a local energy community, and what is the influence of energy sufficiency? The answer is simple when the national electrical grid is taken as an infinite source of storage.
Jonathan Coignard   +3 more
doaj   +1 more source

Biofuels and Energy Self-Sufficiency: Colombian Experience

open access: yes, 2011
The non-renewable nature of fossil fuels combined with the high level of participation within transportation sector in the total consumption of primary energy and atmospheric pollution, have become the primary forces propelling research of alternative sources for vehicles, mainly those sources derived from biomass.
Cortés Marín, Elkin Alonso   +1 more
openaire   +3 more sources

Energy self sufficient house [PDF]

open access: yes, 2015
Bakalářská práce se zabývá problematikou energeticky soběstačných domů. Jedná se o rešerši požadavků a technických aplikací použitelných při návrhu energeticky soběstačného domu.
Hrncsjarová, Hana
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Capacity-constrained renewable power generation development in light of storage cost uncertainty. ESRI Working Paper No. 647 December 2019 [PDF]

open access: yes, 2019
The development of sustainable energy sources and their enabling infrastructures are often met by public opposition, resulting in lengthy planning processes.
Bertsch, Valentin   +2 more
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Self-sufficiency of agriculture in Finland in 1970—1983

open access: yesAgricultural and Food Science, 1986
This study is aimed at considering self-sufficiency and food security in Finland. Self-sufficiency of final products has been over 100 % for a long period. Only self-sufficiency of fruits and vegetables is below 100 % due to the climate. Self-sufficiency
Lauri Kettunen
doaj  

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