Results 51 to 60 of about 8,396,236 (293)
International Journal of Electrical Power & Energy SystemsModular Multilevel Converter (MMC)-based Multi-terminal High-voltage Direct Current (MTDC) systems have gained widespread application in power transmission, where analyzing their wideband stability is critical for enhancing DC grid operational ...
Yanxu Wang +6 more
doaj +1 more source
Analysis of the Environmental Impact in the Life Cycle of a Single-Family House in Poland
Atmosphere, 2022 Buildings consume energy, which is a major contributor to greenhouse gas emissions. In order to reduce their environmental impact, it is important to choose suitable building materials and energy source.
Krzysztof Grygierek +1 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Applying uncertainty considerations to energy conservation equations [PDF]
, 2007 When applying computer simulation tools in practice uncertainties abound, for example in material properties and boundary conditions. To facilitate the quantification of the effects of uncertainties, the differential, factorial and Monte Carlo methods ...
Clarke, Joseph Andrew +3 more
core +1 more source
Buildings, 2023 The present investigation carries out a thermal evaluation of two rooms located in the Royal Hospital of Granada (Rector’s Office). This is a heritage building where have been done studies that allow the as-sessment of possible improvements in future ...
María Paz Sáez-Pérez +5 more
doaj +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Buildings, 2023 Al Ain is the second-largest city in the Abu Dhabi Emirate, and the population of Al Ain has been growing rapidly for the last 50 years. The residential units in Al Ain are arranged using different concepts in relation to household social and economic ...
Lindita Bande +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Energy Conservation for the Simulation of Deformable Bodies [PDF]
IEEE Transactions on Visualization and Computer Graphics, 2013 We propose a novel technique that allows one to conserve energy using the time integration scheme of one's choice. Traditionally, the time integration methods that deal with energy conservation, such as symplectic, geometric, and variational integrators, have aimed to include damping in a manner independent of the size of the time step, stating that ...
Jonathan Su, Rahul Sheth, Ronald Fedkiw
openaire +2 more sources