Results 51 to 60 of about 563,564 (315)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Assessing energy consumption in supply chains

, 2006
The paper addresses the transport activities and associated energy consumption involved in the production and supply of two products: jeans and yoghurt. In the case of jeans, the analysis is from the locations in which cotton is grown, to retail outlets ...
Browne, M., Allen, J., Rizet, C.
core   +1 more source

Research on the Thermo-mechanical Effect of Large-size Cables and its Influence on Insulation Based on Finite Element Method

E3S Web of Conferences, 2018
In order to study the thermo-mechanical effect of large-size cables, the thermal-structural coupling model is established to calculate the stress and deformation of the cables based on finite element method.
Li Shengchong, Wang Fujue, Ma Hongzhong, Xu Honghua, Wang Chunning   +4 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Optimization of joint operation of district and distributed heat sources for effective and reliable heat supply to consumers

E3S Web of Conferences, 2018
The problem of optimal load distribution between district and distributed heat sources (heat sources of prosumers) in the district heating systems are considered. The methodical approach and mathematical model for solving this problem are proposed.
Postnikov Ivan, Stennikov Valery, Penkovskii Andrey   +2 more
doaj   +1 more source

Optimal Tilt Angle and Orientation of Photovoltaic Modules Using HS Algorithm in Different Climates of China

Applied Sciences, 2017
Solar energy technologies play an important role in shaping a sustainable energy future, and generating clean, renewable, and widely distributed energy sources.
Mian Guo, Haixiang Zang, Shengyu Gao, Tingji Chen, Jing Xiao, Lexiang Cheng, Zhinong Wei, Guoqiang Sun   +7 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Topology Identification Method for Low-Voltage Distribution Node Networks Based on Density Clustering Using Smart Meter Real-Time Measurement Data

IEEE Access
Correctly identifying the topology of a low-voltage distribution network aids in its management by power companies. However, the low collection rate and poor quality of the customer data collected by smart meters create difficulties in the application of
Fengshun Jiao, Zhikeng Li, Jingwen Ai, Haisen Yang, Yongsheng Deng, Duo Li, Weijie Gao, Zhaoyang Lai, Xieli Fu   +8 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source