Results 41 to 50 of about 249,548 (304)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A review of the sources, distribution sequences, and health risks associated with exposure to atmospheric polycyclic aromatic hydrocarbons

Cogent Engineering, 2023
Atmospheric polycyclic aromatic hydrocarbons (PAHs) are associated with adverse health effects in exposed populations. Understanding PAH pollution in ambient air and its adverse impacts is essential for developing effective actions for combating air ...
Godfred Safo-Adu, Francis Attiogbe, Ismaila Emahi, Francis Gorman Ofosu   +3 more
doaj   +1 more source

Sustainable Materials for Energy

Nanomaterials
The sustainable production of energy without environmental footprints is a challenge of paramount importance to satisfy the ever-increasing global demand and to promote economic and social growth through a greener perspective. Such awareness has significantly stimulated worldwide efforts aimed at exploring various energy paths and sources, in ...
Filippo Agresti, Giuliano Angella, Humaira Arshad, Simona Barison, Davide Barreca, Paola Bassani, Simone Battiston, Carlo Alberto Biffi, Maria Teresa Buscaglia, Giovanna Canu, Francesca Cirisano, Silvia Maria Deambrosis, Angelica Fasan, Stefano Fasolin, Monica Favaro, Michele Ferrari, Stefania Fiameni, Jacopo Fiocchi, Marco Fortunato, Donatella Giuranno, Parnian Govahi, Jacopo Isopi, Francesco Montagner, Cecilia Mortalò, Enrico Miorin, Rada Novakovic, Luca Pezzato, Daniela Treska, Ausonio Tuissi, Barbara Vercelli, Francesca Villa, Francesca Visentin, Valentina Zin, Maria Losurdo   +33 more
openaire   +3 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Multiple Criteria Decision-Making as an Operational Conceptualization of Energy Sustainability

, 2021
There is a broad international consensus about the urgency of promoting a strong change towards energy models that are less dependent on non-renewable energy sources, more equitable, and truly environmentally friendly.
José Carlos Romero, Pedro Linares
core   +1 more source

Reaction of ethylene over a typical Fischer‐Tropsch synthesis Co/TiO2 catalyst

Engineering Reports, 2020
In order to identify the potential reaction paths of C2H4 and their product distribution in Fischer‐Tropsch synthesis (FTS), a series of experiments were designed over a Co/TiO2 catalyst in the absence of CO.
Yusheng Zhang, Mgcini Tshwaku, Yali Yao, Jianli Chang, Xiaojun Lu, Xinying Liu, Diane Hildebrandt   +6 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Comparisons of the physicochemical and functional properties of commercially and traditionally processed sago starch

MATEC Web of Conferences, 2017
Commercial sago starch was obtained from nearby supermarket while traditional sago starch (lemantak) was obtained from local wet-market. In this study, the physicochemical (moisture content, colour, particle size and microstructure) and functional ...
Mustafa Kamal M., Baini R., Mohamaddan S., Henry Ragai A.R., Soh Fong L., Abdul Rahman N., Mili N., Taib S.N.L., Othman A.K., Abdullah M.O.   +9 more
doaj   +1 more source

Pyrolysis of plastic waste into diesel engine-grade oil

Scientific African, 2023
The pyrolysis of plastic waste to fuel will lead to greener waste management, ensure sustainability and serve as an alternative energy source. This study seeks to convert plastic waste into diesel engine-grade oil as an alternative energy source for ...
N.K. Ndiaye, N.S.A. Derkyi, E. Amankwah
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source