Results 31 to 40 of about 1,923,066 (316)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Energy optimization of multiprocessor systems on chip by voltage selection

open access: yes, 2007
Dynamic voltage selection and adaptive body biasing have been shown to reduce dynamic and leakage power consumption effectively. In this paper, we optimally solve the combined supply voltage and body bias selection problem for multiprocessor systems with
Eles, Petru Ion,   +9 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Building Integration of Active Solar Energy Systems in the Urban Fabric: Façade Renovation Using Building Integration of Active Solar Systems and Effects on Thermal Comfort in Public Spaces

open access: yes, 2021
In the last few years, the negative externalities brought about by climate change are becoming evident. Moreover, in 2030, 80% of the world’s population will live in cities, opposed to today’s 50%, which explains the fact that cities are responsible for ...
Vassiliades C.   +2 more
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Special Issue "Renewable Energy and Energy Storage Systems"

open access: yes, 2022
Dear Colleagues, This Special Issue covers the state of the art of the following renewable energy and energy storage systems topics: solar energy, wind energy, biomass and bioenergy, hydro power, tidal and wave energy, geothermal energy, mechanical ...
Abdul-Ghani Olabi   +2 more
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

IMPORTANCY OF ENERGY STORAGE SYSTEM IN ENERGY SYSTEM

open access: yes
The increasing integration of renewable energy sources into power systems poses new challenges for operators. To maintain system quality and reliability, the incorporation of energy storage systems (ESSs) stands out as a promising solution. This article delves into the current and emerging trends and technologies of grid-connected ESSs.
Ergashov, K.A., Khaqikov, A.U.
openaire   +2 more sources

Clean energy Australia report 2014 [PDF]

open access: yes, 2015
The review of the Renewable Energy Target (RET), which was announced in February 2014 and continued beyond the end of the year, essentially froze new investment in large-scale renewable energy in Australia last year.
Clean Energy Council
core  

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