Results 71 to 80 of about 1,923,066 (316)
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
International Transactions on Electrical Energy Systems
doaj +1 more source
Evaluation of Energy Conservation Measures by Model Simulation [PDF]
Numerous energy conservation measures are being implemented into the air handler units of today's commercial buildings. The economizer cycle has proven potential, and has become increasingly more common.
Giebler, T.; Liu, M.; Claridge, D. E.
core
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
International Transactions on Electrical Energy Systems
doaj +1 more source
Energy performance assessment of HVAC systems by inspection and monitoring [PDF]
The paper discusses the collection and processing of energy performance data as part of the inspection of HVAC systems, aimed at identifying technically feasible and cost-effective Energy Conservation Opportunities (ECO), as required by EPBD.
Silvi, Chiara +2 more
core
Hibernus: sustaining computation during intermittent supply for energy-harvesting systems [PDF]
A key challenge to the future of energy-harvesting systems is the discontinuous power supply that is often generated. We propose a new approach, Hibernus, which enables computation to be sustained during intermittent supply. The approach has a low energy
Balsamo, Domenico +8 more
core +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
International Transactions on Electrical Energy Systems
doaj +1 more source
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source

