Results 41 to 50 of about 6,092,270 (213)

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Impact assessment of greenhouse gas trading on electricity production industry [PDF]

, 2009
Electricity markets constitute an important and rapidly developing research field in the area of energy economics. Deregulation and other organizational advances in international level have boosted electricity markets allowing customers to choose their ...
Tatsiopoulos, Ilias, Kapetanakis, Eleftherios, Tolis, Athanasios, Avraam, Kleopatra, Rentizelas, Athanasios, Varotsis, Nikolaos   +5 more
core   +2 more sources

A Review of Agent-Based Models for Energy Commodity Markets and Their Natural Integration with RL Models

Energies
Agent-based models are a flexible and scalable modeling approach employed to study and describe the evolution of complex systems in different fields, such as social sciences, engineering, and economics.
Silvia Trimarchi, Fabio Casamatta, Laura Gamba, Francesco Grimaccia, Marco Lorenzo, Alessandro Niccolai   +5 more
doaj   +1 more source

Greenhouse Gas Emissions Trading in Europe. Conditions for environmental credibility and economic efficiency. Report of the CEPS Task Force on emission trading and the new EU climate change policy. CEPS Task Force Reports No. 43, 1 October 2002 [PDF]

, 2002
Emissions trading has been shunned for a long time by policy-makers in the European Union as an instrument of environmental policy. It was the Kyoto Protocol that put emissions trading firmly on the EU agenda for the first time.
Legge, Thomas., Egenhofer, Christian
core  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Decentralized trading mechanism of shared energy storage in a residential community considering preference of trading subjects

Energy Reports, 2022
With the decrease in energy storage costs and the popularization of the shared economy principle, shared energy storage (SES) has been gradually deployed in the residential community to reduce energy costs.
Weiqiang Qiu, Tian Zhou, Shuyang Yu, Jien Ma, Tianhan Zhang, Shengyuan Liu, Zhenzhi Lin   +6 more
doaj   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Virtual Power Plant Quotation Strategy Based on Information Gap Decision Theory

Zhongguo dianli
To further enhance the regulatory potential of distributed energy resource (DER), based on the information gap decision theory (IGDT), the bidding methods for virtual power plants (VPPs) participating in demand response (DR) strategies are divided into ...
Mengfei XIE, Gaoquan MA, Bin LIU, Zhenning PAN, Yunfeng SHANG   +4 more
doaj   +1 more source

Application of Blockchain Technology in Energy Trading: A Review

Frontiers in Energy Research, 2021
As blockchain and energy trading have become hot topics in industry and academia, this paper presents a brief literature regarding the blockchain-based energy trading in the fields of energy trading with blockchain.
Hongbiao Li, Fan Xiao, Lixin Yin, Fengtong Wu   +3 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source