Results 111 to 120 of about 2,431,851 (303)
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
EnergiesBifacial photovoltaic technology is made up of solar cells with the ability to generate electrical power on both sides of the cell (front and rear), consequently, they generate more energy in the same area compared to conventional or monofacial solar ...
Angel Eduardo Villarreal-Villela +6 more
doaj +1 more source
Kirigami-inspired automatically self-inclining bifacial solar cell arrays to enhance energy yield under both sunny and cloudy conditions. [PDF]
iScience, 2022 Yun MJ, Sim YH, Lee DY, Cha SI.
europepmc +1 more source
Simulations of slow positron production using a low energy electron accelerator
, 2011 Monte Carlo simulations of slow positron production via energetic electron interaction with a solid target have been performed. The aim of the simulations was to determine the expected slow positron beam intensity from a low energy, high current electron
A. Kinomura +10 more
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Searching for $\Xi_{cc}^+$ in Relativistic Heavy Ion Collisions
, 2016 We study the doubly charmed baryon $\Xi_{cc}^+$ in high energy nuclear collisions. We solve the three-body Schroedinger equation with relativistic correction and calculate the $\Xi_{cc}^+$ yield and transverse momentum distribution via coalescence ...
He, Hang, Zhao, Jiaxin, Zhuang, Pengfei
core +2 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
The influence of combined low-strength ultrasonics and micro-aerobic pretreatment process on methane generation and sludge digestion: Lipase enzyme, microbial activation, and energy yield. [PDF]
Ultrason Sonochem, 2021 Rashvanlou RB +5 more
europepmc +1 more source