Results 141 to 150 of about 243,920 (259)

Adjunctive interferon-γ immunotherapy for the treatment of HIV-associated cryptococcal meningitis: a randomized controlled trial.

, 2012
BACKGROUND: Interferon-gamma (IFNγ) is of key importance in the immune response to Cryptococcus neoformans. Mortality related to cryptococcal meningitis remains high, and novel treatment strategies are needed.
Bekker, Linda-Gail, Bicanic, Tihana, Harrison, Thomas S, Jarvis, Joseph N, Meintjes, Graeme, Rebe, Kevin, Schutz, Charlotte, Williams, Anthony, Williams, Gertrude Ntombomzi, Wood, Robin   +9 more
core   +1 more source

Proteomic Analysis of Regulated Dendritic Cell Endosomes Reveals Dynamic Adaptation to Antigen Uptake and Cross‐Presentation

European Journal of Immunology, Volume 56, Issue 2, February 2026.
Phagocytosis of yeast activates recruitment of proteases and trafficking factors from the secretory and endosomal pathways to the IRAP compartment and subsequently phagosomes, promoting cross‐presentation. In the absence of Sec22b, IRAP endosome and phagosome maturation to late endosomes is accelerated.
Alice Senni, Louise Grumbach, Sara Ceccacci, Mathieu Frechin, Nicolas Goudin, Ida Chiara Guerrera, Barbara Bertocci, Peter van Endert   +7 more
wiley   +1 more source

1 enfant sur 30 conçu par assistance médicale à la procréation en France

, 2018
É. Rochebrochard
semanticscholar   +1 more source

La perception des devoirs à domicile chez les enseignants et les parents: La pratique, l’autonomie, la relation famille-école [PDF]

, 2015
Le travail mené dans le cadre de mon mémoire est un questionnement sur les apports et les difficultés des devoirs à domicile, plus précisément comment les enseignants et les parents les perçoivent.
Clénin, Julien, Meister, Gilles
core  

Luxembourg and France: Comparable Family Benefits, Comparable Fertility Levels? [PDF]

The economic theory of the family as proposed by Becker (1981, 1991) predicts clearly the relationship between income (especially the mother's income) and fertility. Indeed, it assesses that an income effect and a substitution effect could coexist, whose
REINSTADLER Anne
core   +1 more source

Recovery from symptoms using an extensively hydrolyzed formula with synbiotic in infants with presumed cow's milk allergy

Journal of Pediatric Gastroenterology and Nutrition, Volume 82, Issue 2, Page 605-614, February 2026.
Abstract Objective Extensively hydrolyzed formulas (eHF) are the first‐line approach for cow's milk protein allergy (CMPA). This study evaluated the effects of eHF with synbiotic eHF (SeHF) on the general condition and symptoms of presumed CMPA infants during the initial 4‐week exclusion diet period.
Anaïs Lemoine, Florence Villard‐Truc, Imene Ait Mohamed Amar, François Payot   +3 more
wiley   +1 more source

L'évaluation des habiletés mathématiques de l'enfant : inventaire critique des outils disponibles

Glossa, 2014
L’évaluation d’un enfant en difficulté mathématique comporte plusieurs étapes tout aussi importantes les unes que les autres : l’entretien d’anamnèse pour identifier les besoins de l’enfant et de sa famille ; l’évaluation des capacités mathématiques ...
Anne LAFAY, Marie-Catherine Saint-Pierre, Joël MACOIR   +2 more
doaj  

Missense Variants in the Second Transmembrane Domain of TMEM17 Disrupt Its Stability and Function and Lead to a Wide Phenotypic Spectrum of Ciliopathies

Clinical Genetics, Volume 109, Issue 2, Page 305-315, February 2026.
Missense variants in TMEM17 disrupt its localization and function at the ciliary transition zone, leading to a wide range of ciliopathy phenotypes, from OFD6 and Joubert syndromes to Meckel syndrome. ABSTRACT Ciliopathies are rare genetic disorders characterized by significant genetic and phenotypic variability.
Lucile Boutaud, Chunmei Li, Candice Moncler, Laure Verlin, Meriem Garfa‐Traoré, Nicolas Bourgon, Dhruvin Akbari, Jeanne Porée, Valentina Serpieri, Marine Panza, Lynda Haddad, Patrick Nitschké, Jacqueline Aziza, Cristina Matt, Enza Maria Valente, Patricia Gargallo, Charlotte Dubucs, Tania Attié‐Bitach, Michel R. Leroux, Sophie Thomas   +19 more
wiley   +1 more source

ATAD3 duplications bridge mitochondrial diseases and Aicardi–Goutières syndrome

Developmental Medicine &Child Neurology, Volume 68, Issue 2, Page 287-294, February 2026.
ATAD3 locus duplications cause a severe neonatal mitochondrial disorder with neuroimaging features resembling interferonopathies, and suggest a mitochondrial nucleic acid‐triggered interferon response. Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.16446 Abstract A recurrent 68‐kb heterozygous duplication of the ATAD3 locus ...
Pauline Planté‐Bordeneuve, Claire‐Marine Bérat, Sylvain Hanein, Cyril Gitiaux, ATAD3 Study Group, Julie Steffann, Isabelle Desguerre, Agnès Rötig, Nathalie Boddaert, Giulia Barcia, Brian Sperelakis‐Beedham, Zahra Assouline, Marie‐Thérèse Abi‐Warde, Rukhshona Abdullazoda, Agnès Guichet, Céline Bris, Aurélien Caux, Marlène Rio, Jérémy Bertrand, Pauline Gaignard, Alice Lepelley, Arnold Munnich, Manuel Schiff, Isabelle Desguerre, Agnès Rötig, Nathalie Boddaert, Giulia Barcia   +26 more
wiley   +1 more source

A nationwide 12‐month observatory of automated insulin delivery shows improved glucose control, sustained adoption, and reduced acute severe events

Diabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 1179-1190, February 2026.
Abstract Aims A nationwide observational study was conducted to assess the 12‐month effectiveness of AID systems in the routine care of people with Type 1 diabetes (PwT1D). Methods All PwT1D, adults, and children, who initiated AID between January 1, 2022, and December 31, 2022, were included across 79 centres.
Jean‐Pierre Riveline, Jean‐Baptiste Julla, Elisabeth Bonnemaison, Michael Joubert, Sandrine Lablanche, Agnès Sola Gazagnes, Delphine Demarsy, Didier Gouet, Pauline Schaepelynck, Chloé Amouyal, Fabienne Dalla Vale, Anne Schletzer‐Mari, Sylvaine Clavel, Anne Spiteri, Catherine Campinos, Sandrine Favre, Igor Tauveron, Laurence Mathivon, Sophie Borot, Guy Fagherazzi, Marc D. Breton, Jean‐François Gautier, Eric Renard, for the OB2F study group, Jean‐Pierre Riveline, Manal Al Masri‐Shbat, Emmanuel Cosson, Isabela Banu, Michael Joubert, Agnès Sola Gazagnes, Gaetan Prevost, Sandrine Lablanche, Pauline Schaepelynck, Charles Thivolet, Nicolas Chevalier, Sophie Borot, Bruno Guerci, Elise Bismuth, Jacques Beltrand, Delphine Demarsy, Emmanuelle Bourrinet, Didier Gouet, Lucien Marchand, Louis Gerbaud‐Morlaes, Salha Fendri, Sylvaine Clavel, René Valero, Emmanuel Sonnet, Blandine Delenne, Jean‐Paul Donnet, Emma Carreira, Cedric Fagour, Camille Vatier, Rosine Guintrand, Luc Rakotoarisoa, Aurélie Carlier, Anne Spiteri, Igor Tauveron, Lemoine Amal, Letitia Pantalone, Anne Schletzer, Karen Berthelon, Natacha Germain, Françoise Latil Plat, Aroua Temessek, Marie Mansilla, Lorraine Thomesse, Fabienne Dalla Valle, Anne‐Cécile Paepegaey, Nadège Bachere, Candace Ben Signor, Samy Hadjadj, Thanh Lan Dangduy, Mathieu Giraud, Sandrine Favre, Joëlle Dupont, Anna Flaus Furmaniuk, Laure Houdon Nguyen, Patricia Pigeon Kherkiche, Anne‐Cécile Gauthier, Anne Vambergue, Alina Radu, Sandra Pochelu, Abine Baron, Chloé Amouyal, Jennifer Allain‐Cohen, Mariana Geamanu, Florent Verdier, Yannis Chartier, Nathalie Garrec, Annie Sfez, laurence Mathivon, Christine Rouby, Emeline Renard, Agnès Tamboura, Leïla Mchirgui, PH Emilie Georget, Elise Pinto da Rocha, Laure Oilleau‐Barral   +98 more
wiley   +1 more source