Results 141 to 150 of about 125,757 (235)

High frequency of CD95+/CD45RA− regulatory T cells defines an immunosuppressive profile associated with MDS progression

British Journal of Haematology, Volume 208, Issue 6, Page 1993-2003, June 2026.
Summary Dynamic interactions between mutated haematopoietic cells and immune cells are key drivers of myelodysplastic neoplasms (MDS) initiation and progression. Regulatory T cells (Tregs) are central mediators of immunosuppression in MDS. We thus aimed to characterize Treg subpopulations in the bone marrow (BM) of MDS patients and to explore their ...
Romain Vazquez, Nicolas Deredec, Ismael Boussaid, Pierre Boncoeur, Camille Knosp, Amandine Houvert, Loria Zalmai, Chloe Friedrich, Carole Almire, Charles Dussiau, Lise Willems, Rudy Birsen, Justine Decroocq, Didier Bouscary, Olivier Kosmider, Shahram Kordasti, Michaela Fontenay, Yannick Simoni, Nicolas Chapuis   +18 more
wiley   +1 more source

Cutis Marmorata Telangiectatica Congenita: An Atypical Clinical Presentation of Vascular Anomalies. [PDF]

Acta Derm Venereol
El Fekih I, Fraitag S, Kuentz P, Carbonelle-Puscian A, Boccara O.   +4 more
europepmc   +1 more source

Enhancing antitumour response to proteasome inhibitors with inhibitors of insulin‐degrading enzyme, a new molecular vulnerability in multiple myeloma

British Journal of Pharmacology, Volume 183, Issue 12, Page 3355-3376, June 2026.
Inhibitors of insulin‐degrading enzyme boost PI cytotoxicity through an increased sensitivity of proteasome to PI inhibitors, induction of ISR, DNA damage and Myc down‐regulation. They overcome PI resistance in vitro and induce tumour regression in vivo.
Laetitia Lesire, Rebecca Deprez‐Poulain, Damien Bosc, Florence Leroux, Valerie Landry, Sarah Ourabah, Morgane Tardy, Clara Maillard, Ronan Gealageas, Julie Dumont, Adrien Herledan, Sandrine Warenghem, Manon Cruette, Celine Lenglart, Alexandre Biela, Catherine Piveteau, Eva De Smedt, Catharina Muylaert, Wenguang Liang, Elvira Garcia De Paco, Elina Alaterre, Sara Ovejero, Nicolas Robert, Fabien Delahaye, Wei‐Jen Tang, Peter van Endert, Elke De Bruyne, Jérôme Moreaux, Benoit Deprez   +28 more
wiley   +1 more source

[The diagnostic interval of childhood cancer and household socio-economic status in Burkina Faso: a descriptive and exploratory cross-sectional study]. [PDF]

Pan Afr Med J
Ida A, Kouéta F, Kaboret SD, Ouédraogo I, Ouedraogo OM, Zerbo R, Traoré PA.   +6 more
europepmc   +1 more source

Three‐year outcomes of repeated botulinum neurotoxin A injections to the lower extremities in young children with spastic cerebral palsy in GMFCS levels I to III

Developmental Medicine &Child Neurology, Volume 68, Issue 6, Page 792-799, June 2026.
In this study, we followed a group of children 2 to 6 years old with spastic cerebral palsy functioning in GMFCS levels I–III, over 3 years. Sixty‐five received BoNT‐A and 59 did not. Repeated BoNT‐A injections over 3 years were not associated with improvements in gross motor function or passive ankle dorsiflexion. Daily step counts, favouring the BoNT‐
Darcy Fehlings, Emma Bohn, Lauren Switzer, Charles H. Goldsmith, Unni Narayanan, Peter L. Rosenbaum, F. Virginia Wright, Gary Foster, CP‐BoNT‐A Study Group, Timothy Carey, Mark Mason, Ronit Mesterman   +11 more
wiley   +1 more source

<i>COCH</i>-Related Hearing Loss in a French Cohort: Novel Variants and Genotype-Phenotype Correlations. [PDF]

Genes (Basel)
Balogoun R, Serey-Gaut M, Pingault V, Lemiere I, Lina-Granade G, Delplancq G, Guerrot AM, Toutain A, Dupin-Deguine D, Legendre M, Colin E, Loundon N, Jonard L, Marlin S.   +13 more
europepmc   +1 more source

Les expériences de fin de vie des enfants

peer reviewedÀ travers les récits des enfants, ce livre nous invite à un voyage au cœur des expériences les plus intimes et mystérieuses de la vie, de la conception à la mort.
Fawer-Caputo, Christine, FRIEDEL, Marie
core  

A quelle discipline appartiennent les enfants?

, 2012
Nous signalons la préparation de cette journée d’études : « A quelle discipline appartiennent les enfants ? Croisements, échanges et reconfigurations de la recherche autour de l’enfance ? ».
Mathilde Lévêque
core  

Intravenous immunoglobulin and febrile status epilepticus in children with Dravet syndrome: A retrospective multicentre study

Developmental Medicine &Child Neurology, Volume 68, Issue 6, Page 857-863, June 2026.
This multicenter retrospective study evaluated the use of intravenous immunoglobulin (IVIG) in 14 children with Dravet syndrome as a preventive strategy against febrile status epilepticus. Over a 6‐month period, IVIG was associated with a significant reduction in hospitalizations for febrile status epilepticus.
Romane Marc, Nicole Chemaly, Mathieu Kuchenbuch, Caroline Espil‐Taris, Elodie Lametery, Hélène Maurey, Sylviane Peudenier, Sylvie Nguyen The Tich, Rima Nabbout, Claire Bar   +9 more
wiley   +1 more source

MRI Evaluation of Graft Remodeling After Transphyseal Anterior Cruciate Ligament Reconstruction in Pediatric Patients: A 5-Year Follow-up. [PDF]

Orthop J Sports Med
de Pesters C, Staali L, Laval A, Flumian C, Maupoint E, Faruch M, Accadbled F.   +6 more
europepmc   +1 more source