Results 151 to 160 of about 386,776 (309)

Clinical Course and Predictors of Biologic Therapy, Hospitalisation and Surgery: A Five‐Year Prospective Study in Newly Diagnosed Inflammatory Bowel Disease

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
In this large multicentre Spanish inception cohort, biologics/JAK inhibitors were frequently used during the first 5 years after inflammatory bowel disease diagnosis and were associated with reduced hospitalisation risk, although not with lower abdominal surgery rates.
Ana Garre   +308 more
wiley   +1 more source

Eosinophilic Oesophagitis and Incidence of Gastrointestinal Cancer: A Population‐Based Cohort Study

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
Among 9115 patients with eosinophilic oesophagitis in Denmark, excess gastrointestinal cancer in the first year after diagnosis most likely reflected diagnostic work‐up. Beyond 1 year, oesophageal adenocarcinoma and hepatocellular carcinoma remained more frequent than expected; most patients with oesophageal cancer had prior Barrett's oesophagus ...
Gencer Kurt   +4 more
wiley   +1 more source

Personal Birth Experiences and Clinician Attitudes About Cesarean Birth: A Cross‐Sectional Study With Female Labor and Delivery Unit Staff

open access: yesBirth, EarlyView.
Labor and delivery staff's personal experiences with birth are associated with their attitudes about clinical practice. We conducted a cross‐sectional survey of female labor and delivery staff employed at birthing hospitals in Arkansas. A total of 378 staff (physicians, nurses and midwives) from 29 facilities (of 33 birthing hospitals) participated in ...
Tanvangi Tiwari   +6 more
wiley   +1 more source

Tryptase Locus Variation Contributes to Normal‐Range Basal Serum Tryptase Variability and Is Associated With Anaphylaxis

open access: yesClinical &Experimental Allergy, EarlyView.
Tryptase locus variation explains normal‐range baseline serum tryptase differences and is associated with Hymenoptera venom anaphylaxis, independent of clonal mast cell disease and HαT. ABSTRACT Background Increased basal serum tryptase level (BST) is associated with anaphylaxis.
Manca Svetina   +6 more
wiley   +1 more source

Mitigating the human link in emerging reptile fungal pathogen transmission

open access: yesConservation Biology, EarlyView.
Abstract Handling wild reptiles is common among amateur herpetology enthusiasts, professional researchers, social media influencers, and photographers. However, the potential for these interactions to spread diseases that threaten wild reptiles remains underappreciated.
Patrick S. Champagne   +4 more
wiley   +1 more source

¿Aumenta la exposición prenatal al paracetamol el riesgo de trastorno del espectro autista y trastorno por déficit de atención con hiperactividad? Una revisión paraguas y un meta‐meta‐análisis

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Este meta‐metaanálisis sintetiza la evidencia disponible sobre la exposición prenatal al paracetamol y los desenlaces del neurodesarrollo. Los análisis crudos sugieren pequeñas asociaciones con el trastorno del espectro autista (TEA) y el trastorno por déficit de atención e hiperactividad (TDAH); sin embargo, estas asociaciones se atenúan de forma ...
Hoda Tayebi‐Hillali   +5 more
wiley   +1 more source

Duración de la remisión sostenida tras el tratamiento de inducción con nutrición enteral exclusiva y azatioprina en pacientes con enfermedad de Crohn

open access: yesAnales de Pediatría, 2021
Alicia Isabel Pascual Pérez   +4 more
doaj   +1 more source

Metformin Use Is Associated With Better Cognitive Performance in Older Adults With Type 2 Diabetes: Exploratory Analysis of Vitamin B12 and Methylmalonic Acid Pathways in NHANES 2011–2014

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Metformin, the first‐line treatment for Type 2 diabetes mellitus (T2DM), may be neuroprotective but also lowers serum vitamin B12 by ~19%, raising concern that B12 depletion could offset this benefit. We used modern exploratory causal mediation methods in a nationally representative sample to test whether vitamin B12 and methylmalonic ...
Danial Fotros   +2 more
wiley   +1 more source

Ligand binding represses bacterial histidine kinase activity by inhibiting its dimerization

open access: yesThe FEBS Journal, EarlyView.
PdtaS is a kinase in the pathogen Mycobacterium tuberculosis that senses copper and nitric oxide and controls virulence gene expression, but how the kinase senses these compounds was unclear. We show that PdtaS is active as a dimer with each monomer phosphorylating the other in trans.
Gaurav D. Sankhe   +6 more
wiley   +1 more source

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