Results 31 to 40 of about 358,362 (254)
Parasites & Vectors, 2019 Background A question of epidemiological relevance in Chagas disease studies is to understand Trypanosoma cruzi transmission cycles and trace the origins of (re)emerging cases in areas under vector or disease surveillance.
Diana P. Wehrendt +8 more
doaj +1 more source
Empoderando a las personas con enfermedad mental mediante el fomento de empleo
, 2021 Las personas con discapacidad tienen que superar grandes obstáculos para conseguir acceder a un empleo. A pesar de los avances realizados en los últimos años en favor de la inserción laboral, principalmente protagonizados por las entidades de la economía
Agifes +4 more
core
Macrophage‐derived MLKL in alcohol‐associated liver disease: Regulation of phagocytosis
Hepatology, EarlyView., 2022 EtOH causes leaky gut allowing bacteria and PAMPs into the liver, resulting in hepatic inflammation and injury. We demonstrate that LPS induces STAT1‐mediated expression and phosphorylation of MLKL in macrophages and identify a novel function that myeloid MLKL translocates to phagosomes and lysosomes and regulates phagocytosis, which contributes to the
Xiaoqin Wu +16 more
wiley +1 more source
Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird +9 more
wiley +1 more source
The NADPH oxidase NOX4 regulates redox and metabolic homeostasis preventing HCC progression
Hepatology, EarlyView., 2022 Loss of NOX4 in HCC tumor cells induces metabolic reprogramming in a Nrf2/MYC‐dependent manner to promote HCC progression. Abstract Background and Aims The NADPH oxidase NOX4 plays a tumor‐suppressor function in HCC. Silencing NOX4 confers higher proliferative and migratory capacity to HCC cells and increases their in vivo tumorigenic potential in ...
Irene Peñuelas‐Haro +14 more
wiley +1 more source
Revista de Gastroenterología de México, 2017 La incidencia y la prevalencia de la enfermedad inflamatoria intestinal (EII) se han incrementado en los últimos años en varios países de Latinoamérica. Existe una necesidad de concientizar a gastroenterólogos y a la población en general para poder tener
J.K. Yamamoto-Furusho +10 more
doaj +1 more source
Arthritis Care &Research, EarlyView.Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh +5 more
wiley +1 more source
Revista da Sociedade Brasileira de Medicina Tropical, 1987 Se describen los resultados entomológicos de un estúdio sobre transmiswn del Tripanosoma cruzi realizado en un caserío rural de Argentina. Se determino la prevalencia de infección elperfil alimentario de los Triatoma infestans domiciliados ...
Cristina Wisnivesky-Colli +7 more
doaj +1 more source
Enfermedad tromobembólica venosa en enfermedades autoinmunes
, 2022 It is widely accepted that venous thromboembolic disease is more frequent in patients with autoimmune conditions than in the general population. The RIETE registry is the largest database that includes subjects with documented thromboembolic disease. Within the variables that they include, there is a specific category with different autoimmune diseases.
openaire +3 more sources
High Health Care Utilization Preceding Diagnosis With Juvenile Idiopathic Arthritis
Arthritis Care &Research, EarlyView.Objective Although early diagnosis improves long‐term outcomes, patients with juvenile idiopathic arthritis (JIA) often experience prolonged, circuitous paths to diagnosis. To inform diagnostic improvement, we sought to characterize health care utilization in the year preceding diagnosis. Methods We identified 10,021 patients with an incident diagnosis
Anna Costello +5 more
wiley +1 more source