Results 81 to 90 of about 874,388 (342)

A Short Peptide Inhibitor of Measles Virus Fusion Protein that Exhibits Passive Membrane Permeability

open access: yesChemMedChem, EarlyView.
Fusion inhibitor peptide (FIP) is a known small peptide capable of inhibiting measles virus infection. In this study, hydrogen‐to‐fluorine substitution is employed to derivatize FIP, leading to the discovery of a FIP derivative with enhanced inhibitory activity and passive membrane permeability.
Ziwei Gao   +5 more
wiley   +1 more source

Major Organic Involvement in Women with Fabry Disease in Argentina

open access: yesThe Scientific World Journal, 2018
Fabry disease (FD) is an X-linked lysosomal storage disorder resulting from the deficiency or absence of the alpha galactosidase A enzyme. Organic involvement in men is well known, but in women it is controversial, partly due to the random X-chromosomes ...
Fernando Perretta   +2 more
doaj   +1 more source

RGS14 (414)-mediated prevention of an episodic memory loss: a study of molecular mechanism [PDF]

open access: yes, 2015
A large proportion of human populations suffer memory impairments either caused by normal aging or afflicted by diverse neurological and neurodegenerative diseases. Memory enhancers and other drugs tested so far against memory loss have failed to produce
Navarro Lobato, Irene
core   +1 more source

RAB19, SERPINB9P1, and Pancreatitis in Patients Taking Azathioprine in Routine Clinical Practice: Genome and Transcriptome‐Wide Association Studies

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Azathioprine is used to treat several inflammatory and autoimmune diseases. However, its use is limited by serious adverse events, including acute pancreatitis. Prior studies have found an association between the HLA region and thiopurine‐induced acute pancreatitis (TIAP); however, in clinical practice, many patients with pancreatitis do not meet this ...
Shailja C. Shah   +16 more
wiley   +1 more source

Early diagnosis of Alzheimer's disease: update on combining genetic and brain-imaging measures. [PDF]

open access: yes, 2000
Diagnosis of Alzheimer's disease is often missed or delayed in clinical practice; thus, methods to improve early detection would provide opportunities for early intervention, symptomatic treatment, and improved patient function.
Small, GW
core   +1 more source

Myomaker and Myomixer are required for craniofacial myoblast fusion in zebrafish

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Craniofacial and trunk skeletal muscles are derived from different progenitor populations during development. Trunk skeletal muscles contain mostly multinucleated myofibers that are formed through myoblast fusion. However, myoblast fusion in craniofacial muscles and its molecular regulation are not well understood.
Zhanxiong Zhang   +3 more
wiley   +1 more source

Enfermedad de Parkinson y musicoterapia [PDF]

open access: yes, 2016
La enfermedad de Parkinson es la segunda enfermedad neurodegenerativa en España producida por una alteración de la sustancia negra del cerebro. Esta afectación da lugar a un déficit de dopamina, causante de la sintomatología de esta enfermedad.
Fernández Franco, Laura
core  

Expert Perspective: Hematologic Malignancies and Vasculitis

open access: yes
Arthritis &Rheumatology, EarlyView.
Michelle L. Robinette, Hetty E. Carraway
wiley   +1 more source

Dynamics of postnatal bone development and epiphyseal synostosis in the caprine autopod

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Bones develop to structurally balance strength and mobility. Bone developmental dynamics are influenced by whether an animal is ambulatory at birth. Precocial species, which are ambulatory at birth, develop advanced skeletal maturity in utero and experience postnatal development under mechanical loading.
Christopher J. Panebianco   +8 more
wiley   +1 more source

Enfermedad trofoblástica

open access: yesRevista Colombiana de Obstetricia y Ginecología, 1985
En 248 casos de enfermedad trofoblástica en el Hospital Universitario de Cali-Col. S.A., se da una incidencia de 1 caso por 4.348 embarazos.La mayoría de las pacientes son de nivel socio-económico bajo.Se encontraron 218 molas, 12 corioadenomas y 18 coriocarcionomas.El mayor número de casos estuvo entre los 20-30 años.El síntoma predominante fue la ...
openaire   +3 more sources

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