Results 81 to 90 of about 1,076,986 (335)

Substituent‐Based Modulation of Self‐Assembly and Immunogenicity of Amphipathic Peptides

Advanced Science, EarlyView.
This study systematically investigates how positional and subtle changes, such as substituents on the phenyl ring attached to short amphipathic peptides, influence their self‐assembly, fibril morphology, and immunogenic responses. ABSTRACT Self‐assembled peptide‐based biomaterials provide versatile platforms for biomedical uses, featuring customizable ...
Anirban Das, Ushasi Pramanik, Elise M. Brown, Chih‐Yun Liu, Huan Gong, Jonathan Fascetti, Mark Gibson, Samuel Stealey, Silviya P. Zustiak, Cory Berkland, Piyoosh Sharma, Meredith E. Jackrel, Mark A. White, Jai S. Rudra   +13 more
wiley   +1 more source

Caracterización de la enfermedad renal crónica en adultos mayores

Revista Colombiana de Nefrología, 2018
Introducción: la enfermedad renal crónica (ERC) genera numerosos gastos sanitarios y es altamente prevalente en ancianos.Objetivo: caracterizar pacientes adultos mayores con ERC residentes en el municipio Consolación del Sur, Cuba, en el período ...
J. C. Candelaria-Brito, Carlos Gutiérrez-Gutiérrez, Héctor Demetrio Bayarre-Vea, C. Cruz, D. M. D. Oca, Orestes Labrador-Mazón   +5 more
semanticscholar   +1 more source

GATA3 Deletion Associated With Juvenile Idiopathic Arthritis: Expanding the Phenotypic Spectrum of Hypoparathyroidism, Sensorineural Deafness, and Renal Dysplasia (HDR) Syndrome

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Hypoparathyroidism, sensorineural deafness, and renal dysplasia (HDR) syndrome is caused by pathogenic variants in the GATA3 gene located on chromosome 10p14. Here we present a 10‐year‐old girl with HDR syndrome who also has oligoarticular juvenile idiopathic arthritis (JIA).
Lauren N. Meiss, Amanda V. Karam, Julia Shalen, David E. Tunkel, Belina Y. Yi, Kelsey S. Guthrie, Emily M. Kudalkar, Anna E. Patrick, Sonja A. Rasmussen   +8 more
wiley   +1 more source

Enfermedad de Parkinson y musicoterapia [PDF]

, 2016
La enfermedad de Parkinson es la segunda enfermedad neurodegenerativa en España producida por una alteración de la sustancia negra del cerebro. Esta afectación da lugar a un déficit de dopamina, causante de la sintomatología de esta enfermedad.
Fernández Franco, Laura
core  

Psychiatric Comorbidities and Treatment Modalities in Children With Osteogenesis Imperfecta: A Systematic Review of Mental Health

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT To evaluate the prevalence of psychiatric signs and symptoms and describe psychotherapeutic and psychopharmacological interventions among children with osteogenesis imperfecta (OI). PRISMA guidelines were followed, and the study was registered in PROSPERO (CRD42024588284). Studies (n = 1419) were identified across five databases.
Julia M. Morales, Camille F. Villar, Beatriz Varman, Gianna M. Colombo, Danqi Li, Sarah J. Sadek, Marie‐Eve Robinson, Chaya N. Murali, Kara Ayers, Jocelyn Gomez, Brendan Lee, V. Reid Sutton, Eric A. Storch, Andrew D. Wiese   +13 more
wiley   +1 more source

Major Organic Involvement in Women with Fabry Disease in Argentina

The Scientific World Journal, 2018
Fabry disease (FD) is an X-linked lysosomal storage disorder resulting from the deficiency or absence of the alpha galactosidase A enzyme. Organic involvement in men is well known, but in women it is controversial, partly due to the random X-chromosomes ...
Fernando Perretta, Norberto Antongiovanni, Sebastián Jaurretche   +2 more
doaj   +1 more source

Aspectos y consideraciones generales en la enfermedad inflamatoria intestinal durante la pandemia por COVID-19

Revista de Gastroenterología de México, 2020
Resumen: Hasta este momento, la evidencia disponible sugiere que los pacientes con enfermedad inflamatoria intestinal (EII) no tienen un mayor riesgo de desarrollar COVID-19.
J.L. de León-Rendón, C. Hurtado-Salazar, J.K. Yamamoto-Furusho   +2 more
doaj   +1 more source

Mechanisms of Mitochondrial Toxicity and Cytotoxicity Caused by Pseudomonas aeruginosa Pyocyanin in Human Nasal Epithelial Cells

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Pseudomonas aeruginosa is an opportunistic pathogen in cystic fibrosis‐related chronic rhinosinusitis (CF‐CRS) that produces phenazine metabolites pyocyanin and 1‐hydroxyphenazine (1‐HP), which may have detrimental effects on mitochondria, reactive oxygen species (ROS), Ca2+ signaling, and apoptosis.
Joel C. Thompson, April Park, Yobouet Ines Kouakou, Zoey A. Miller, Nabil F. Darwich, Nithin D. Adappa, James N. Palmer, Ryan M. Carey, Robert J. Lee   +8 more
wiley   +1 more source

External Validation of Cardiovascular Risk Scores in the Southern Cone of Latin America: Which Predicts Better? [PDF]

, 2018
Introducción: La estimación inexacta del riesgo cardiovascular poblacional puede llevar a un manejo inadecuado de las intervenciones médicas preventivas, como, por ejemplo, el uso de estatinas.
Danaei, Goodarz, Gulayin, Pablo Elías, Gutierrez, Laura, Irazola, Vilma, Lanas, Fernando, Poggio, Rosana, Ponzo, Jaqueline, Rubinstein, Adolfo Luis   +7 more
core  

Consenso mexicano para el diagnóstico y tratamiento de la colitis ulcerosa crónica idiopática

Revista de Gastroenterología de México, 2018
Resumen: Estas guías constituyen una actualización de las guías publicadas en 2007. Desde ese año, los conocimientos acerca de la fisiopatología, así como las opciones terapéuticas, han evolucionado rápidamente, con la aprobación de nuevos agentes, la ...
J.K. Yamamoto-Furusho, Y. Gutiérrez-Grobe, J.G. López-Gómez, F. Bosques-Padilla, J.L. Rocha-Ramírez   +4 more
doaj   +1 more source