Results 31 to 40 of about 277,636 (191)

Fluctuation of Anti–Domain 1 and Anti–β2‐Glycoprotein I Antibody Titers Over Time in Patients With Persistently Positive Antiphospholipid Antibodies

open access: yesArthritis &Rheumatology, Volume 75, Issue 6, Page 984-995, June 2023., 2023
Objective The present study was undertaken to longitudinally evaluate titers of antibodies against β2‐glycoprotein I (anti‐β2GPI) and domain 1 (anti‐D1), to identify predictors of variations in anti‐β2GPI and anti‐D1 titers, and to clarify whether antibody titer fluctuations predict thrombosis in a large international cohort of patients who were ...
Cecilia B. Chighizola   +92 more
wiley   +1 more source

Enfermedades reumáticas y alergias, la dualidad del sistema inmunológico

open access: yesRevista Alergia México, 2021
Las enfermedades reumáticas autoinmunes son trastornos multisistémicos que afectan principalmente las articulaciones y los músculos; algunos ejemplos de estas afecciones son la artritis reumatoide, el lupus eritematoso sistémico y el síndrome de Sjögren.
Gabriela Athziri Sánchez-Zuno   +5 more
doaj   +1 more source

IL6/sIL6R regulates TNFα-inflammatory response in synovial fibroblasts through modulation of transcriptional and post-transcriptional mechanisms

open access: yesBMC Molecular and Cell Biology, 2020
Introduction The clinical efficacy of specific interleukin-6 inhibitors has confirmed the central role of IL6 in rheumatoid arthritis (RA). However the local role of IL6, in particular in synovial fibroblasts (SF) as a direct cellular target to IL6/sIL6R
Alvaro Valin   +10 more
doaj   +1 more source

TFAM-deficient mouse skin fibroblasts – an ex vivo model of mitochondrial dysfunction

open access: yesDisease Models & Mechanisms, 2021
Mitochondrial dysfunction associates with several pathological processes and contributes to chronic inflammatory and ageing-related diseases. Mitochondrial transcription factor A (TFAM) plays a critical role in maintaining mtDNA integrity and function ...
Manuel J. Del Rey   +7 more
doaj   +1 more source

La importancia del laboratorio en el diagnóstico del síndrome de Sjögren primario

open access: yesRevista de la Facultad de Ciencias Médicas de Córdoba, 2009
El síndrome de Sjögren (SS) es una enfermedad autoinmune sistémica que se caracteriza fundamentalmente por la presencia de xeroftalmía y xerostomía debido a la infiltración de las glándulas lagrimales y salivares por células linfoplasmocitarias. Al igual
Pilar Brito-Zerón   +6 more
doaj   +1 more source

Global excellence in rheumatology in Latin America: The case of systemic lupus erythematosus

open access: yesFrontiers in Medicine, 2023
Systemic lupus erythematosus (SLE) affects more severely non-White populations, due to their genetic background and sociodemographic characteristics.
Manuel F. Ugarte-Gil   +9 more
doaj   +1 more source

Pellagra ohne Niacinmangel?

open access: yes, 2022
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 20, Issue 9, Page 1228-1230, September 2022.
Ines Bertlich   +5 more
wiley   +1 more source

Necrotizing Sarcoid Granulomatosis: A Disease Not to be Forgotten

open access: yesCase Reports in Medicine, Volume 2020, Issue 1, 2020., 2020
Sarcoidosis is a systemic granulomatous disease of unknown aetiology characterised by the appearance of noncaseifying epithelioid granulomas in the affected organs, most commonly the lungs, skin, and eyes (Iannuzzi et al. 2007). Necrotizing Sarcoid Granulomatosis (NGS) is a rare and little‐known form of disease, which also presents nodular lung lesions,
A. I. Parejo-Morón   +6 more
wiley   +1 more source

Senescent synovial fibroblasts accumulate prematurely in rheumatoid arthritis tissues and display an enhanced inflammatory phenotype

open access: yesImmunity & Ageing, 2019
Background Accumulation of senescent cells has been associated with pro-inflammatory effects with deleterious consequences in different human diseases.
Manuel J. Del Rey   +9 more
doaj   +1 more source

inmunidad en enfermedades autoinmunes

open access: yesArchivos de Neurociencias, 2020
En este artículo se revisaron cuatro de las enfermedades autoinmunes más prevalentes en México. Nos enfocamos especialmente en la actividad del sistema inmune (linfocitos T y B) para entender cómo una alteración da lugar a una cascada de reacciones auto-lesivas para el individuo.
Martin Eduardo Torres-Velasco   +3 more
openaire   +1 more source

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