Results 31 to 40 of about 418,665 (179)

Leisure‐Time Physical Activity on Age‐Modelled Trajectories of Body Mass Index and Obesity Risk Throughout Life: Multivariable Regression and Mendelian Randomization Analyses Using Electronic Health Record Data From the CORDELIA‐Catalunya Study

Diabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 8925-8935, October 2026.
ABSTRACT Aims To assess whether self‐reported leisure‐time physical activity, moderate‐to‐vigorous leisure‐time physical activity, and genetically determined cardiorespiratory fitness are associated with age‐related BMI trajectories and incident obesity. Methods We pooled 14 993 adults (30–90 years; 52.7% women; cohorts: REGICOR‐ACRISC, ILERVAS, ARTPER)
Javier Hernando‐Redondo, Anna Camps‐Vilaró, Roberto Elosua, Eleonora Fornara, Marcelino Bermúdez‐López, Pere Torán‐Monserrat, Ainara Jiménez‐Navarro, José M. Valdivielso, Víctor M. López‐Lifante, Tomàs Salas‐Fernández, Serafí Cambray, Raquel Cruz, Jaume Marrugat, Álvaro Hernáez   +13 more
wiley   +1 more source

Efecto del cilostazol en la maduración de fístulas arteriovenosas en pacientes con enfermedad renal crónica

Revista Mexicana de Angiolog�a
Antecedentes: El cilostazol tiene efectos sobre el endotelio vascular que podrían favorecer la maduración de la fístula arteriovenosa al inhibir la agregación plaquetaria, producir vasodilatación y reducir la proliferación vascular. Objetivo: Evaluar la relación entre el uso de cilostazol y la maduración de fístulas arteriovenosas.
Carlos J. Bernal-González, Jaime G. López-Taylor, Claudia E. Mojica-Rodríguez, Ma. Fernanda Sánchez-Gutiérrez, César U. Cervantes-Domínguez, Hilda P. Ledezma-Verdeja, Tonatiuh González-Heredia   +6 more
openaire   +2 more sources

Topliss‐Guided Optimization of Acetanilide‐Based Soluble Epoxide Hydrolase Inhibitors: Exploring the Pentafluorosulfanyl Group as a Potency‐Enhancing Motif

ChemMedChem, Volume 21, Issue 16, 27 August 2026.
Can an amide analog retain the high potency of the classic urea motif in soluble epoxide hydrolase inhibitors? Through a single unconventional switch, the introduction of the underexplored pentafluorosulfanyl group into an amide analog of TPPU, the authors restored high inhibitory potency.
Alba López‐Ruiz, Eugènia Pujol, Cristian Ramos, Valeria Rizzo, Christophe Morisseau, Cristina Val, Tiziana Ginex, Javier Vázquez, Sandra Codony, Andreea L. Turcu, Belén Pérez, Elena Sáez, Antonio Pineda‐Lucena, Bruce D. Hammock, F. Javier Luque, M. Isabel Loza, José Brea, Santiago Vázquez   +17 more
wiley   +1 more source

Prevalence of chronic kidney disease in Peruvian primary care setting

BMC Nephrology, 2017
Background Chronic Kidney Disease (CKD) is a worldwide public health problem. There are few studies in Latin America, especially in primary care settings.
Percy Herrera-Añazco, Alvaro Taype-Rondan, María Lazo-Porras, E. Alberto Quintanilla, Victor Manuel Ortiz-Soriano, Adrian V. Hernandez   +5 more
doaj   +1 more source

Impact of environmental neurotoxic: current methods and usefulness of human stem cells

Heliyon, 2020
The development of central nervous system is a highly coordinated and complex process. Any alteration of this process can lead to disturbances in the structure and function of the brain, which can cause deficits in neurological development, resulting in ...
Andreea Rosca, Raquel Coronel, Miryam Moreno, Rosa González, Andreea Oniga, Alberto Martín, Victoria López, María del Carmen González, Isabel Liste   +8 more
doaj   +1 more source

Satisfacción y percepciones sobre aspectos de la ciudad que afectan la salud, por nivel socioeconómico, 2010-2019, en Lima Metropolitana

Revista Peruana de Medicina Experimental y Salud Pública, 2022
Se buscó caracterizar la satisfacción y percepciones de los residentes de Lima Metropolitana sobre distintos aspectos de la ciudad que pueden afectar su calidad de vida y salud, identificando diferencias por nivel socioeconómico (NSE) y cambios en el ...
Victoria Cavero, Akram Hernández-Vásquez, J. Jaime Miranda, Patricia Alata, Mariana Alegre, Francisco Diez-Canseco   +5 more
doaj   +1 more source

Factores de riesgo cardiovascular y su relación con la progresión de la enfermedad venosa crónica

Revista Mexicana de Angiolog�a
Antecedentes: La progresión de la enfermedad venosa crónica (EVC) suele estar ligada a factores de riesgo que son motivo de investigación aun sin asociación clara. Objetivo: Identificar si los factores de riesgo cardiovascular (FRC) impactan la progresión de la EVC. Método: Análisis retrospectivo observacional de datos clínicos y epidemiológicos de 314
Leopoldo E. Padilla-Hernández, Omar A. Hernández-Hurtado, Carlos Flores-Ramírez, Joaquín M. Santoscoy-Ibarra, Luis B. Enríquez-Sánchez, Raúl A. Hinojos-Flotte, Dalia G. Delgado-Ortega, Yarazi M. Carrasco-Arredondo   +7 more
openaire   +2 more sources

Hypertension at 5 months postpartum in women with gestational diabetes

Ultrasound in Obstetrics &Gynecology, Volume 68, Issue 2, Page 202-210, August 2026.
ABSTRACT Objective Gestational diabetes mellitus (GDM) is associated with future maternal cardiovascular disease, independent of the development of Type‐2 diabetes mellitus. As a major cardiovascular risk factor, we examined the incidence and predictors of hypertension at 5 months postpartum in women with previous GDM.
C. Gómez Fernández, M. Charakida, M. Moser, R. Breiviene, T. Mansukhani, L. A. Magee, P. von Dadelszen, K. H. Nicolaides   +7 more
wiley   +1 more source

The patient journey for people with dementia and their carers in Peru: From first symptoms to diagnosis and treatment

Alzheimer's &Dementia, Volume 22, Issue 7, July 2026.
Abstract INTRODUCTION We explored how people with dementia (PwD) and their carers navigate Peru's health system for diagnosis and treatment. METHODS We interviewed PwD (n = 4), carers (n = 18), and healthcare workers (n = 17) from four sites. We developed a patient journey map using thematic analysis and participant validation.
Daniela Rossini‐Vilchez, Francisco Jose Tateishi‐Serruto, Christopher Butler, María Sofía Cuba‐Fuentes, Silvana Perez‐Leon, Miriam Lúcar‐Flores, Guillermo Almeida‐Huanca, L. Carolina Olaya‐Silva, J. Jaime Miranda, Maria Kathia Cardenas, Jose Carlos Vera Tudela, Antonio Bernabe‐Ortiz, Rafael A. Calvo, Francisco Diez‐Canseco, Filipa Trigo Landeiro, Graham Moore, Lee White, William Whiteley, María Lazo‐Porras, Jemma Hawkins, the IMPACT Salud Research Group   +20 more
wiley   +1 more source

Rapamycin Partially Reverts Cavernoma Endothelial Cell Phenotype and, When Combined With Lapatinib, Ameliorates Chronic Lesions

Journal of Cellular and Molecular Medicine, Volume 30, Issue 13, July 2026.
ABSTRACT This study investigates the impact of rapamycin and propranolol on cerebral cavernous malformations (CCMs). Employing an unbiased transcriptomic analysis, we aimed to comprehensively elucidate the molecular mechanisms underlying these drug effects.
Mar García‐Colomer, José E. Martínez, Luis Díaz‐Gómez, Miriam Sartages, Eva M. Esquinas‐Román, Cristina Riobello, David Martínez‐Delgado, Diego González‐Pérez, Aurora Gómez‐Durán, Miguel Fidalgo, Marta Varela‐Rey, Celia M. Pombo, Juan Zalvide   +12 more
wiley   +1 more source