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Fasciolosis: una enfermedad emergente
, 2018 La fasciolosis, también conocida con el nombre de distomatosis, es una enfermedad parasitaria que afecta no solo al ganado bovino y ovino sino también al ser humano, debido a que es zoonótica. Está ampliamente distribuida en el mundo, lo que contribuye con su capacidad de afectación a la salud y bienestar animal, lo que origina pérdidas económicas para Perea-Fuentes, Mabel, Díaz-Anaya, Adriana, Pulido-Medellín, Martín Orlando, Bulla-Castañeda, Diana +3 moreopenaire +1 more sourceGenomic and Sex Contributions to Interindividual Variability in Pitavastatin Bioavailability
Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 1, July 2026.ABSTRACT Aim
This study investigates pharmacogenetic determinants of pitavastatin disposition using a candidate‐gene approach. Methods
In 48 healthy volunteers, 138 variants across 40 genes involved in drug metabolism and transport were analysed to assess their relationship with pitavastatin pharmacokinetics, alongside the influence of sex and ...Eva González‐Iglesias, Sofía Moreno‐Pérez de Villar, Dolores Ochoa, Manuel Román, Jesús Novalbos, Samuel Martín‐Vilchez, Alejandro de Miguel, Francisco Abad‐Santos +7 morewiley +1 more sourceRapid generation of prion disease models using AAV‐delivered PrP variants in knockout mice
Brain Pathology, Volume 36, Issue 4, July 2026.We developed a rapid AAV‐based system to generate prion disease models in weeks rather than months. Following systemic AAV9P31 delivery of modified PrP to knockout mice, we achieved brain‐wide expression and successful propagation of both classical (RML) and atypical (GSS‐A117V) prion strains.Maitena San‐Juan‐Ansoleaga, Eva Fernández‐Muñoz, Jorge M. Charco, Enric Vidal, Diego Herrero‐Martínez, Josu Galarza‐Ahumada, Cristina Sampedro‐Torres‐Quevedo, Samanta Giler, Mariví Geijo, Gloria González‐Aseguinolaza, Hasier Eraña, Joaquín Castilla +11 morewiley +1 more sourcePeriweaning failure to thrive syndrome (PFTS): A growing concern in swine health
Porcine Health ManagementBackground Porcine Periweaning Failure to Thrive syndrome (PFTS) is a complex and scarcely investigated syndrome that has been of increasing concern in the swine industry during the last decade.Macarena Rodríguez-Ruiz, Librado Carrasco, Inés Ruedas-Torres, José M. Sánchez-Carvajal, Karola Fristiková, Carmen Álvarez-Delgado, Irene M. Rodríguez-Gómez, Jaime Gómez-Laguna, Francisco J. Pallarés +8 moredoaj +1 more sourceProteomic analysis of granulomas from cattle and pigs naturally infected with Mycobacterium tuberculosis complex by MALDI imaging
Frontiers in ImmunologyMatrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) has recently gained prominence for its ability to provide molecular and spatial information in tissue sections.Fernanda Larenas-Muñoz, José María Sánchez-Carvajal, Inés Ruedas-Torres, Inés Ruedas-Torres, Carmen Álvarez-Delgado, Karola Fristiková, Francisco José Pallarés, Librado Carrasco, Eduardo Chicano-Gálvez, Irene Magdalena Rodríguez-Gómez, Jaime Gómez-Laguna +10 moredoaj +1 more sourcePerceptions of Buprenorphine With Naloxone Treatment and the Fear of Precipitated Withdrawal: A Qualitative Exploration With HIV Prevention Trials Network 094 INTEGRA Participants and Staff
Drug and Alcohol Review, Volume 45, Issue 5, July 2026.ABSTRACT Introduction
Uptake of evidence‐based medication for opioid use disorder (MOUD), including buprenorphine–naloxone, remains low despite the expanding US opioid crisis. This study examined participants' and staff perceptions of adopting and delivering buprenorphine–naloxone on a mobile unit providing integrated MOUD and HIV services for people ...Rose A. Schmidt, Amaya Perez‐Brumer, Peter Davidson, Steve Shoptaw, Nabila El‐Bassel, Philip Andrew, Jayla Harris, Omar Nieto, Sydney Bornstein, Rashaunna Redd, Jessica Yeager, David Goodman‐Meza, Albert L. Hasson, Marc Seigel, Cecile Denis, Renee El‐Krab, Laramie R. Smith, on behalf of the HPTN 094 Team +17 morewiley +1 more sourceNeuropsychiatric Adverse Events Associated With Foslevodopa/Foscarbidopa Continuous Subcutaneous Infusion in Clinical Practice: A Multicenter Study
European Journal of Neurology, Volume 33, Issue 7, July 2026.In 214 patients with advanced Parkinson's disease receiving foslevodopa/foscarbidopa continuous subcutaneous infusion, neuropsychiatric adverse events occurred in 19.2%. Baseline cognitive impairment and hallucinations did not increase risk, whereas preexisting impulse control disorders predicted ICD‐related adverse events.David Campo‐Caballero, Jon Rodriguez‐Antiguedad, Arnau Puig‐Davi, Javier Ruiz‐Martinez, Ana Vinagre‐Aragón, Elisabet Mondragón, Lara Pardina Vilella, Nuria López‐Ariztegui, Nuria Caballol, Guillermo González‐Ortega, Iria Cabo, Rocío García Ramos, Inés Legarda, Marta Blázquez‐Estrada, Pilar Sánchez‐Alonso, Pablo Mir, Juan Carlos Romero Fábrega, Silvia Martí Martinez, María Álvarez Sauco, Diego Santos‐García, DATs‐PD GETM Spanish Registry Group, Nuria López Ariztegui, Maria Isabel Morales Casado, Guillermo Tabar Comellas, Asunción Ávila Rivera, Núria Caballol Pons, Anna Planas‐Ballvé, Alejandro Peral Quirós, Dolors Lozano, Diego Santos García, Jose Manuel Paz González, Carlos Cores Bartolomé, Lucia Belen Samaniego Vinueza, Ángela Solleiro Vidal, Iria Cabo, Alejandro Rivero de Aguilar Pensado, Rocío García Ramos, Ana Fernández Revuelta, Eva López Valdés, Ana Aldaz, Carmen Ribacoba Díaz, Inés Legarda Ramírez, Bàrbara Vives Pastor, María Fuensanta Valero García, Marta Blázquez Estrada, Esther Suárez San Martín, Ciara García Fernández, Pilar Tartiere, Patricia Prendes Fernández, Pilar Sánchez‐Alonso, Sabela Novo Ponte, Elisa Gamo González, Raquel Martín García, Pablo Mir Rivera, Laura Muñoz Delgado, Astrid Daniela Adarmes Gómez, Elena Ojeda Lepe, Silvia Jesús Maestre, Daniel Macías García, Fátima Carrillo García, Ana María Castellano Guerrero, Manuela San Eufrasio Martínez, Cristina Pérez Calvo, María López González, Andrés García Herruzo, Cristina Gómez Rapela, Lorena Garrote Espina, Natalia González Rojas, Juan Carlos Romero Fábrega, Francisco Escamilla Sevilla, Lucía Triguero Cueva, Carlos Javier Madrid Navarro, Silvia Martí Martínez, María Álvarez Sauco, Eric Freire Álvarez, Jessica González Ardura, Belén Castaño García, Antonio Sánchez Rodríguez, Déborah Alonso Modino, Jesús Norelis Lorenzo Brito, Maria Esther Rojas Pérez, Carolina Hernández Javier, Jorge Hernández Vara, Maria Victoria González, Sara Belmonte, Débora María Cerdán Santacruz, Amelia Mendoza Rodríguez, Ana Castrillo Sanz, Lorena Caballero Sánchez, Claudia Gómez López de San Román, Álvaro Sánchez‐Ferro, Pablo Rábano Suárez, Antonio Méndez Guerrero, Daniel Pérez Rangel, Jesús Ramírez, Cristina del Álamo Criado, Javier Ruíz Martínez, Elisabet Mondragón Rezola, Ana Vinagre Aragón, Lara Pardina Vilella, David Campo Caballero, Ana Belén Perona Moratalla, Gustavo Fernández‐Pajarín, Maria Pilar Gil Villar, Agustín Sancho Saldana, Laura Quibus Requena, Ángela Monterde Ortega, Juan Carlos Gómez Esteban, Tamara Fernández Valle, Marta Ruiz López, Beatriz Tijero Merino, Susana Cantarero Duque, Guillermo González‐Ortega, Esther Cubo Delgado, Beatriz Alegre García, Lydia López Manzanares, Inés Muro, Elena Casas Peña, Pablo Lorenzo Barreto, Emma Cañada Lahoz, Sara Lozano Veiga, Lydia Vela, Irene Martínez‐Torres, Carlos Morata‐Martínez, Raquel Baviera‐Muñoz, Marina Campins Romeu, Isabel Sastre Bataller, Elena Navarro Mocholí, Roberto López Blanco, Sonia Escalante Arroyo, Tania Delgado Ballestero +130 morewiley +1 more sourceA Sequence‐Based Update on Amino Acid Substitutions in Influenza Polymerase Acidic Protein in Europe That Alter Baloxavir Susceptibility From 2009 to 2025
Influenza and Other Respiratory Viruses, Volume 20, Issue 7, July 2026.ABSTRACT Background
Influenza causes 650,000 deaths, 3–5 million hospitalizations, and 1 billion cases worldwide each year. There is a limited repertoire of antivirals available to tackle this burden, highlighting the risk of developing resistance to current drugs.Alejandro Martín‐Toribio, Inés Inchausti‐Moya, Marina Toquero‐Asensio, Sonia García‐Díaz, Javier Sanchez‐Martinez, Carla Rodriguez‐Crespo, Silvia Galindo‐Carretero, Raquel Iglesia‐Aparicio, Celia Lopez‐Gonzalo, Ana Antón‐Contreras, Silvia Rojo‐Rello, Marta Dominguez‐Gil, Marta Hernández, Jose M. Eiros, Estanislao Nistal‐Villan, Iván Sanz‐Muñoz +15 morewiley +1 more sourceCharacteristics and Risk Factors Associated With Hospitalization and Severe Disease in Patients Aged ≥ 60 Years With Human Metapneumovirus Infection Over Three Consecutive Seasons (2021–2024) in Valladolid, Spain. The VALLAVIRUS Study
Influenza and Other Respiratory Viruses, Volume 20, Issue 7, July 2026.ABSTRACT Background
Human metapneumovirus (hMPV) is a respiratory pathogen often underestimated in the elderly. Although studies suggest it causes around 10% of respiratory hospitalizations in the United States, national and local data remain scarce.Iván Sanz‐Muñoz, Silvia Galindo‐Carretero, Marina Toquero‐Asensio, Alejandro Martín‐Toribio, Raquel Iglesia‐Aparicio, Celia López‐Gonzalo, Diana Rodríguez‐González, Laura Tamayo‐Pérez, Javier Sánchez‐Martínez, Carla Rodríguez‐Crespo, Alberto Caballero‐García, Marta Domínguez‐Gil, Silvia Rojo‐Rello, José María Eiros +13 morewiley +1 more source