Results 111 to 120 of about 388,150 (220)

Fasciolosis: una enfermedad emergente

open access: yes, 2018
La fasciolosis, también conocida con el nombre de distomatosis, es una enfermedad parasitaria que afecta no solo al ganado bovino y ovino sino también al ser humano, debido a que es zoonótica. Está ampliamente distribuida en el mundo, lo que contribuye con su capacidad de afectación a la salud y bienestar animal, lo que origina pérdidas económicas para
Perea-Fuentes, Mabel   +3 more
openaire   +1 more source

Genomic and Sex Contributions to Interindividual Variability in Pitavastatin Bioavailability

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 139, Issue 1, July 2026.
ABSTRACT Aim This study investigates pharmacogenetic determinants of pitavastatin disposition using a candidate‐gene approach. Methods In 48 healthy volunteers, 138 variants across 40 genes involved in drug metabolism and transport were analysed to assess their relationship with pitavastatin pharmacokinetics, alongside the influence of sex and ...
Eva González‐Iglesias   +7 more
wiley   +1 more source

Rapid generation of prion disease models using AAV‐delivered PrP variants in knockout mice

open access: yesBrain Pathology, Volume 36, Issue 4, July 2026.
We developed a rapid AAV‐based system to generate prion disease models in weeks rather than months. Following systemic AAV9P31 delivery of modified PrP to knockout mice, we achieved brain‐wide expression and successful propagation of both classical (RML) and atypical (GSS‐A117V) prion strains.
Maitena San‐Juan‐Ansoleaga   +11 more
wiley   +1 more source

Periweaning failure to thrive syndrome (PFTS): A growing concern in swine health

open access: yesPorcine Health Management
Background Porcine Periweaning Failure to Thrive syndrome (PFTS) is a complex and scarcely investigated syndrome that has been of increasing concern in the swine industry during the last decade.
Macarena Rodríguez-Ruiz   +8 more
doaj   +1 more source

Proteomic analysis of granulomas from cattle and pigs naturally infected with Mycobacterium tuberculosis complex by MALDI imaging

open access: yesFrontiers in Immunology
Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) has recently gained prominence for its ability to provide molecular and spatial information in tissue sections.
Fernanda Larenas-Muñoz   +10 more
doaj   +1 more source

Perceptions of Buprenorphine With Naloxone Treatment and the Fear of Precipitated Withdrawal: A Qualitative Exploration With HIV Prevention Trials Network 094 INTEGRA Participants and Staff

open access: yesDrug and Alcohol Review, Volume 45, Issue 5, July 2026.
ABSTRACT Introduction Uptake of evidence‐based medication for opioid use disorder (MOUD), including buprenorphine–naloxone, remains low despite the expanding US opioid crisis. This study examined participants' and staff perceptions of adopting and delivering buprenorphine–naloxone on a mobile unit providing integrated MOUD and HIV services for people ...
Rose A. Schmidt   +17 more
wiley   +1 more source

Neuropsychiatric Adverse Events Associated With Foslevodopa/Foscarbidopa Continuous Subcutaneous Infusion in Clinical Practice: A Multicenter Study

open access: yesEuropean Journal of Neurology, Volume 33, Issue 7, July 2026.
In 214 patients with advanced Parkinson's disease receiving foslevodopa/foscarbidopa continuous subcutaneous infusion, neuropsychiatric adverse events occurred in 19.2%. Baseline cognitive impairment and hallucinations did not increase risk, whereas preexisting impulse control disorders predicted ICD‐related adverse events.
David Campo‐Caballero   +130 more
wiley   +1 more source

Evaluation of the Effectiveness of Eugenol and MS-222 as Anesthetics in Zebrafish in Repeated Exposures and Post-Anesthesia Behaviour

open access: yesAnimals
The increasing use of the zebrafish (Danio rerio) in scientific experiments has made it necessary to implement anesthesia protocols guaranteeing minimum pain and suffering for these animals and ensuring the reliability of the results obtained from their ...
Nahúm Ayala-Soldado   +4 more
doaj   +1 more source

A Sequence‐Based Update on Amino Acid Substitutions in Influenza Polymerase Acidic Protein in Europe That Alter Baloxavir Susceptibility From 2009 to 2025

open access: yesInfluenza and Other Respiratory Viruses, Volume 20, Issue 7, July 2026.
ABSTRACT Background Influenza causes 650,000 deaths, 3–5 million hospitalizations, and 1 billion cases worldwide each year. There is a limited repertoire of antivirals available to tackle this burden, highlighting the risk of developing resistance to current drugs.
Alejandro Martín‐Toribio   +15 more
wiley   +1 more source

Characteristics and Risk Factors Associated With Hospitalization and Severe Disease in Patients Aged ≥ 60 Years With Human Metapneumovirus Infection Over Three Consecutive Seasons (2021–2024) in Valladolid, Spain. The VALLAVIRUS Study

open access: yesInfluenza and Other Respiratory Viruses, Volume 20, Issue 7, July 2026.
ABSTRACT Background Human metapneumovirus (hMPV) is a respiratory pathogen often underestimated in the elderly. Although studies suggest it causes around 10% of respiratory hospitalizations in the United States, national and local data remain scarce.
Iván Sanz‐Muñoz   +13 more
wiley   +1 more source

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