Results 31 to 40 of about 12,244 (197)

Laparoscopic Methylene Blue Photodynamic Therapy for Intraabdominal Infection: A Preclinical Feasibility Study in a Rabbit Model of Perforated Appendicitis

open access: yesLasers in Surgery and Medicine, EarlyView.
ABSTRACT Objectives Perforated appendicitis commonly results in intra‐abdominal infection requiring prolonged antibiotic therapy. Intraoperative antimicrobial adjuncts are limited, and photodynamic therapy (PDT) may provide a targeted, resistance‐independent approach.
Timothy M. Baran   +7 more
wiley   +1 more source

Universal and Lineage‐Specific Patterns in the Distribution of ECOD Domain Homology Groups Across Superkingdoms

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Proteins are built from modular domains that serve as fundamental units of structure and evolution. While individual domains have been extensively cataloged, their collective distribution across the lineages of life has remained poorly resolved.
Rui Guo   +5 more
wiley   +1 more source

Differential effects of switching to integrase strand transfer inhibitors on the gut microbiota and markers of HIV disease progression

open access: yesBMC Microbiology
Background Unwanted weight gain is often reported in people living with HIV (PWH) who start on or switch to integrase strand transfer inhibitors (INSTI). Mechanisms are incompletely understood.
Sandra M. Pinto-Cardoso   +10 more
doaj   +1 more source

Caracterización del bienestar en hogares mexicanos de niñas y niños con diarrea, Ensanut Continua 2022

open access: yesSalud Pública de México, 2023
Objetivo. Analizar el nivel de bienestar en los hogares mexicanos de niñas y niños menores de cinco años que presentaron enfermedad diarreica aguda (EDA) en las últimas dos semanas en México, según la Encuesta Nacional de Salud y Nutrición Continua 2022 (
Guadalupe Delgado-Sánchez   +8 more
doaj   +1 more source

Trajectories of medication for opioid use disorder and their impact on HIV testing among people who inject drugs in India: A longitudinal assessment of clinic‐based data

open access: yesAddiction, Volume 120, Issue 4, Page 745-755, April 2025.
Abstract Aims The aim of this study was to identify longitudinal trajectories of medication for opioid use disorder (MOUD) use throughout 1 year following MOUD initiation and to examine the association of trajectory membership with HIV testing among people who inject drugs in India.
Allison M. McFall   +8 more
wiley   +1 more source

Time‐Resolved Multi‐Omics Identify Biomarkers of Immediate Reactions to mRNA Vaccination

open access: yesAllergy, EarlyView.
We compared early vaccine‐induced immune and metabolic signatures and downstream immunity after second and booster BNT162b2 doses in participants with sARs, ISSRs, or no reactions. Neutrophil mobilization, antiviral programs, and robust anti‐S‐antibody responses occurred across reaction groups.
Ana Olivera   +14 more
wiley   +1 more source

Maternal Perinatal Gut Microbiome Is Shaped by Traditional Farming Lifestyle and Associated With Early Childhood Atopic Disease

open access: yesAllergy, EarlyView.
We assessed whether the maternal perinatal gut microbiome and serum SCFA and cord blood SCFA differ between traditional farming and urban dyads. Women following a farming lifestyle had increased microbial diversity, several differentially abundant bacterial species and functional pathways, and increased circulating SCFA. Overall maternal gut microbiome
Erin C. Davis   +7 more
wiley   +1 more source

Distinct Gene Expression Profiles of Ara h 2‐Specific B Cells in Desensitization and Tolerance During Peanut Oral Immunotherapy

open access: yesAllergy, EarlyView.
Gene expression of Ara h 2‐specific B cells over the course of the peanut OIT. Isotype of allergen‐specific B cells changes through OIT towards IgG4. Peanut OIT changes the gene expression of allergen‐specific memory B cells. OIT patients showed increased gene expression for regulatory B cells and immune regulation.
Stephan R. Schneider   +48 more
wiley   +1 more source

Challenges in HIV care at a tertiary hospital repurposed for COVID-19: an observational study (2019–2022)

open access: yesBMC Infectious Diseases
Background The COVID-19 pandemic disrupted global healthcare systems, reducing access to care for people with chronic conditions, including HIV. In Mexico, the National Institute of Respiratory Diseases (INER) was fully repurposed as a COVID-19 referral ...
Karla Alejandra Romero-Mora   +7 more
doaj   +1 more source

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