Results 81 to 90 of about 7,462 (202)

Coordinated regulation of PIEZO2 by alternative splicing, post‐translational modification, membrane trafficking and protein partners

The Journal of Physiology, EarlyView.
Abstract figure legend Regulatory mechanisms such as alternative splicing, post‐translational modification, membrane trafficking, and protein interactions control channel gating, membrane abundance, and overall activity of PIEZO2. Proper regulation supports PIEZO2‐dependent proprioceptive, somatosensory, nociceptive, pruriceptive and interoceptive ...
Eunice I. Oribamise, Qinglu Li, Mary G. Garry   +2 more
wiley   +1 more source

MC BTS: Simultaneously Resolving Magnetization Transfer Effect and Relaxation for Multiple Components

Magnetic Resonance in Medicine, Volume 95, Issue 5, Page 2538-2553, May 2026.
ABSTRACT Purpose To propose a signal acquisition and modeling framework for multi‐component tissue quantification that encompasses transmit field inhomogeneity, multi‐component relaxation and magnetization transfer (MT) effects. Theory and Methods By applying off‐resonance irradiation between excitation and acquisition within an RF‐spoiled gradient ...
Albert Jang, Hyungseok Jang, Nian Wang, Alexey Samsonov, Fang Liu   +4 more
wiley   +1 more source

Accelerating Multiparametric Quantitative MRI Using Self‐Supervised Scan‐Specific Implicit Neural Representation With Model Reinforcement

Magnetic Resonance in Medicine, Volume 95, Issue 5, Page 2963-2979, May 2026.
ABSTRACT Purpose To develop a self‐supervised scan‐specific deep learning framework for reconstructing accelerated multiparametric quantitative MRI (qMRI). Methods We propose REFINE‐MORE (REference‐Free Implicit NEural representation with MOdel REinforcement), combining an implicit neural representation (INR) architecture with a model reinforcement ...
Ruimin Feng, Albert Jang, Xingxin He, Fang Liu   +3 more
wiley   +1 more source

Monocyte LOXHD1 and RHOB Expression Predictive of Progressive Systemic Sclerosis–Associated Interstitial Lung Disease

Arthritis Care &Research, Volume 78, Issue 4, Page 456-468, April 2026.
Objective A leading cause of death among patients with scleroderma (SSc), interstitial lung disease (ILD) remains challenging to prognosticate. The discovery of biomarkers that accurately determine which patients would benefit from close monitoring and aggressive therapy would be an essential clinical tool.
Cristina M. Padilla, Robert Lafyatis, Kevin F. Gibson, Christina Morse, Eleanor Valenzi, Xiaoping Chen, Xiaoyun Li, Yanwu Zhao, Yongseok Park, Dana Ascherman, Jonathan Minden, Robyn Domsic, Yingze Zhang, Daniel J. Kass   +13 more
wiley   +1 more source

Temporal Trends in and Associations With Nonsteroidal Anti‐inflammatory Drug Prescription in Adult and Pediatric Patients With Inflammatory Bowel Disease

Arthritis Care &Research, Volume 78, Issue 4, Page 439-448, April 2026.
Objective Recent inflammatory bowel disease (IBD) treatment guidelines have recommended against nonsteroidal anti‐inflammatory drug (NSAID) use despite prevalent musculoskeletal symptoms and opioid overuse in this population. Given the discordance between changing national guidelines and potential clinical utility, we sought to assess national temporal
Adam S. Mayer, Rui Xiao, Andrew Grossman, Meenakshi Bewtra, Michael D. George, Pamela F. Weiss   +5 more
wiley   +1 more source

Serum Soluble Mediator Signatures of Lupus Nephritis: Histologic Features and Response to Treatment

Arthritis Care &Research, Volume 78, Issue 4, Page 520-527, April 2026.
Objective Lupus nephritis (LN) management remains challenging, and novel noninvasive biomarkers are needed. This study quantified serum soluble mediators in the Accelerating Medicines Partnership (AMP) LN cohort to identify biomarkers of histologic features and treatment response.
Andrea Fava, Catriona A. Wagner, Carla J. Guthridge, Susan Macwana, Wade DeJager, Melissa E. Munroe, Peter Izmirly, H. Michael Belmont, Betty Diamond, Anne Davidson, Paul J. Utz, Michael H. Weisman, Philip M. Carlucci, Maria Dall'Era, Kenneth Kalunian, Chaim Putterman, Jennifer Anolik, Jennifer L. Barnas, David Wofsy, Diane Kamen, Richard A. Furie, Deepak A. Rao, the Accelerating Medicines Partnership Rheumatoid Arthritis and Systemic Lupus Erythematosus Network, Chun‐Hao Lee, Derek Fine, Manny Monroy‐Trujillo, Ummara Shah, Mariko Ishimori, Robert M. Clancy, Michael Belmont, Ming Wu, Nicole Bornkamp, Evan Der, Beatrice Goilav, Nicole Jordan, Daniel Schwartz, James Pullman, David Wofsy, Dawn Smilek, Patti Tosta, Matthias Kretzler, Celine C. Berthier, E. Steve Woodle, Dave Hildeman, Michael Brenner, Michelle Petri, Joel M. Guthridge, Jill Buyon, Judith A. James   +48 more
wiley   +1 more source

Evaluating a Smartphone App–Based Module for Joint Self‐Assessment as a Complementary Tool in Rheumatoid Arthritis Remote Disease Management

ACR Open Rheumatology, Volume 8, Issue 4, April 2026.
Objective The objective of this study was to develop and evaluate a new patient‐facing tool to facilitate patient self‐examination of joints as a complement to telehealth during the management of rheumatoid arthritis (RA). Methods Using a community‐based rheumatology network, we evaluated the efficacy of an in‐app cartoon‐based joint examination module
Swamy Venuturupalli, Jiaxin Jessica He, Mhun‐Jeong Isaac Lee, Talya Koger, Sofia Havadjias, Yogamanas Jinka, Natalie Fortune, Fenglong Xie, Yujie Su, Sandeep K. Sodhi, Neelkamal Soares, Kelly Gavigan, Shilpa Venkatachalam, John Cush, Danielle Ali, William B. Nowell, David Curtis, Rebecca Grainger, Jeffrey R. Curtis   +18 more
wiley   +1 more source

CAPÍTULO 5: Manifestaciones extra musculoesqueléticas en espondiloartritis axial 2: enfermedad inflamatoria intestinal y otras

Revista Argentina de Reumatología
Las enfermedades inflamatorias intestinales (EII), incluyendo la enfermedad de Crohn (EC) y la colitis ulcerosa (CU), se presentan asociadas a la espondiloartritis axial radiográfica (EspAax-r) con una frecuencia reportada entre el 6-14 ...
Rodolfo Peréz Alamino
doaj  

Aine y riesgo cardiovascular: los menos posibles, a la menor dosis posible y durante el menor tiempo posible

Revista Médica Clínica Las Condes, 2014
Antecedentes: Los antünflamatorios no esteroideos (AINE) son ampliamente utilizados en el tratamiento sintomatológico del dolor e inflamación en pacientes con enfermedades musculoesqueléticas, incluida la artrosis.
Ferrán Catalá-López
doaj   +1 more source

Epidermólisis bullosa: cuidados de Enfermería [PDF]

, 2017
La Epidermólisis Bullosa, aun tratándose de una enfermedad de poca incidencia (enfermedad rara), supone un problema de salud con importantes repercusiones para el paciente y su familia, que deben conocerse y ser tratados adecuadamente por los ...
Asensio Mucientes, Lucía
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