Results 11 to 20 of about 150 (115)

Degradomics for large‐scale mechanistic insights on proteases and proteolysis in human health

open access: yesThe FEBS Journal, Volume 293, Issue 13, Page 3881-3898, July 2026.
Proteolysis has an important role in human disease but remains relatively unexplored. Degradomics, the uncovering of proteolysis in tissues, cells, and proteins, uses mass spectrometry‐based terminomics to identify protein termini occurring therein (forward degradomics) and to define the actions of proteases (reverse degradomics).
Daniel R. Martin   +2 more
wiley   +1 more source

Prospective comparison of diagnostic accuracy of ultrasound, PET/CT and DW‐MRI for preoperative assessment of pelvic lymph nodes in cervical cancer patients: results of the CANNES trial

open access: yesUltrasound in Obstetrics &Gynecology, Volume 67, Issue 6, Page 836-851, June 2026.
ABSTRACT Objective To determine whether ultrasound is non‐inferior to positron‐emission tomography/computed tomography (PET/CT) and diffusion‐weighted magnetic resonance imaging (DW‐MRI) in terms of overall diagnostic accuracy for the preoperative assessment of pelvic lymph‐node status in cervical cancer.
F. Frühauf   +14 more
wiley   +1 more source

Caracterización clínica de los casos de dengue hospitalizados en la E.S.E. Hospital ""Antonio Roldán Betancur"", Apartadó, Antioquia, Colombia, 2000.

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2006
Introducción. Desde 1998 se vienen notificando casos de dengue hemorrágico en el municipio de Apartadó y actualmente el dengue se considera endemo-epidémico. Objetivo.
Margarita Arboleda   +3 more
doaj   +1 more source

Impaired angiogenesis in gestational diabetes is linked to succinate/SUCNR1 axis dysregulation in late gestation

open access: yesThe Journal of Physiology, Volume 604, Issue 11, Page 4261-4278, 1 June 2026.
Abstract figure legend Gestational Diabetes Mellitus (GDM) impacts on succinate metabolism and angiogenesis in the umbilical cord endothelium. (Left Panel) Succinate levels increase in both maternal and fetal circulation at delivery, with higher concentrations observed in GDM pregnancies compared to controls during late gestation.
Sergiy Klid   +13 more
wiley   +1 more source

Estrategia de atención al síndrome de flujo vaginal en gestantes. Sancti Spíritus

open access: yesGaceta Médica Espirituana, 2014
Fundamento: las infecciones de trasmisión sexual constituyen un problema de salud en todo el mundo, sin embargo en la provincia se carece de información sobre bases científicas de los resultados de la aplicación de la estrategia para la atención del ...
Ana María Lugo González   +5 more
doaj  

Defining HIV Pre‐Exposure Prophylaxis (PrEP) Persistence: A Scoping Review

open access: yesJournal of the International AIDS Society, Volume 29, Issue 5, May 2026.
ABSTRACT Introduction When assessing the effectiveness of pre‐exposure prophylaxis (PrEP) programmes, interventions, or modalities, it is important to understand patterns of PrEP use. Continued use of PrEP is frequently referred to as PrEP “persistence.” But persistence is not defined consistently, and differences impact the interpretation of study ...
Sarah E. Rutstein   +5 more
wiley   +1 more source

Balancing Risk and Hope: Insights Into Pregnancy Outcomes in Pulmonary Arterial Hypertension

open access: yesPulmonary Circulation, Volume 16, Issue 2, April 2026.
This cohort study demonstrates that vasoreactive status identifies a low‐risk subgroup in PAH pregnancies, characterised by zero major or minor adverse events, unlike the significant complications seen in non‐vasoreactive patients. These distinct outcomes underscore the need for risk‐stratified, personalized management for pregnant women with PAH ...
Teresa Segura de la Cal   +14 more
wiley   +1 more source

GATA3 Deletion Associated With Juvenile Idiopathic Arthritis: Expanding the Phenotypic Spectrum of Hypoparathyroidism, Sensorineural Deafness, and Renal Dysplasia (HDR) Syndrome

open access: yesAmerican Journal of Medical Genetics Part A, Volume 200, Issue 3, Page 733-737, March 2026.
ABSTRACT Hypoparathyroidism, sensorineural deafness, and renal dysplasia (HDR) syndrome is caused by pathogenic variants in the GATA3 gene located on chromosome 10p14. Here we present a 10‐year‐old girl with HDR syndrome who also has oligoarticular juvenile idiopathic arthritis (JIA).
Lauren N. Meiss   +8 more
wiley   +1 more source

Integration of HIV Status in Cancer Surveillance in South Africa: A Call for Action

open access: yesCancer Medicine, Volume 15, Issue 3, March 2026.
ABSTRACT Background Human immunodeficiency virus (HIV) increases the risk of developing cancer. We aimed to assign HIV status to cancers diagnosed in public laboratories recorded in the National Cancer Registry (NCR) in South Africa, guided by HIV counselling and testing guidelines.
Carole Metekoua   +9 more
wiley   +1 more source

T‐bet Fate Mapping Reveals Gestational Stage‐Specific Transcriptional Adaptation of Decidual NK Cells

open access: yesAmerican Journal of Reproductive Immunology, Volume 95, Issue 3, March 2026.
ABSTRACT Problem Natural killer (NK) cells are critical regulators of immune balance at the maternal–fetal interface. T‐bet (Tbx21) is a key transcription factor shaping NK cell effector functions, yet its role in decidual NK (dNK) cell adaptation across gestation remains unclear.
Mona A. Mohamed   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy