Results 11 to 20 of about 97 (45)

Comparative In vitro Metabolism of Enflicoxib in Dogs, Rats, and Humans: Main Metabolites and Proposed Metabolic Pathways. [PDF]

Drug Metab Lett, 2021
Background: Enflicoxib is a non-steroidal anti-inflammatory drug of the coxib family characterized by a long-lasting pharmacological activity that has been attributed to its active metabolite E-6132. Objective: The aim of this work was to explore enflicoxib biotransformation in vitro in humans, rats and dogs, and to determine its metabolic pathways.
Solà J, Menargues À, Homedes J, Salichs M, Serafini MT, Encina G.   +5 more
europepmc   +5 more sources

Review for "Pharmacology of enflicoxib, a new coxib drug: Efficacy and dose determination by clinical and pharmacokinetic‐guided approach for the treatment of osteoarthritis in dogs based on an acute arthritis induction model"

, 2021
null Giovanna Lucrezia Costa
core   +5 more sources

Editorial: Exploring anesthetic risk: challenges and solutions in veterinary medicine. [PDF]

Front Vet Sci
Portier K, Senior M.
europepmc   +6 more sources

Decision letter for "Pharmacology of enflicoxib, a new coxib drug: Efficacy and dose determination by clinical and pharmacokinetic‐guided approach for the treatment of osteoarthritis in dogs based on an acute arthritis induction model"

, 2021
core   +4 more sources

Musculoskeletal adverse events in dogs receiving bedinvetmab (Librela). [PDF]

Front Vet Sci
ObjectivesTo conduct a specialist-led disproportionality analysis of musculoskeletal adverse event reports (MSAERs) in dogs treated with bedinvetmab (Librela™) compared to six comparator drugs with the same indication. Furthermore, to report the findings
Farrell M, Waibel FWA, Carrera I, Spattini G, Clark L, Adams RJ, Von Pfeil DJF, De Sousa RJR, Villagrà DB, Amengual-Vila M, Paviotti A, Quinn R, Harper J, Clarke SP, Jordan CJ, Hamilton M, Moores AP, Greene MI.   +17 more
europepmc   +3 more sources

Artificial Intelligence Approach in Machine Learning-Based Modeling and Networking of the Coronavirus Pathogenesis Pathway. [PDF]

Curr Issues Mol Biol
The coronavirus pathogenesis pathway, which consists of severe acute respiratory syndrome (SARS) coronavirus infection and signaling pathways, including the interferon pathway, the transforming growth factor beta pathway, the mitogen-activated protein ...
Tanabe S, Quader S, Ono R, Tanaka HY, Yamamoto A, Kojima M, Perkins EJ, Cabral H.   +7 more
europepmc   +3 more sources

Author response for "Pharmacology of enflicoxib, a new coxib drug: Efficacy and dose determination by clinical and pharmacokinetic‐guided approach for the treatment of osteoarthritis in dogs based on an acute arthritis induction model"

, 2021
null Josep‐Maria Cendrós, null Marta Salichs, null Gregorio Encina, null Jose Miguel Vela, null Josep M. Homedes   +4 more
openaire   +2 more sources

Pregabalin Alleviates Anxiety and Fear in Cats during Transportation and Veterinary Visits—A Clinical Field Study [PDF]

, 2023
Cats frequently suffer from anxiety related to travel and veterinary visits. One sequela is avoidance of veterinary visits and lack of adequate veterinary care. The objective of this study was to test clinical efficacy and safety of a novel formulation
Aspegren J., Korpivaara M., Lamminen T., Overall K. L., Palestrini C.   +4 more
core   +1 more source

The standards of reporting trials in pets (PetSORT): Explanation and elaboration [PDF]

, 2023
Well-designed randomized controlled trials (RCTs) provide the best evidence of the primary research designs for evaluating the effectiveness of interventions.
Annette M. O'Connor, Audrey Ruple, Jan M. Sargeant, Laura E. Selmic   +3 more
core   +1 more source

Experiência Profissionalizante nas vertentes de Investigação e Farmácia Comunitária [PDF]

, 2022
O presente relatório para obtenção do Grau de Mestre em Ciências Farmacêuticas encontrase dividido em dois capítulos. O Capítulo I é referente à componente de investigação e consiste numa revisão bibliográfica denominada “Estudo dos efeitos tóxicos de ...
Neto, Catarina Isabel Moura
core