Results 71 to 80 of about 36,296 (305)

Research and Simulation of Control Strategy of the Regenerative Braking Energy Recycle of Hybrid Vehicle

Jixie chuandong, 2015
Aiming at the characteristic of hybrid vehicle powertrain system,a new control strategy of regenerative braking is put forward based on the classification of braking intensity,in developing the simulation model,many vital factors,such as the initial ...
Gao Lijie
doaj  

Wheel movement during braking [PDF]

, 2002
YesAn experimental study of wheel movement arising from compliance in the front suspension and steering system of a passenger car during braking is presented.
Day, Andrew J., Klaps, J.
core  

Studying Macromolecular Composition in Cell–Cell Interfaces Using 3D Membrane Reconstitution Systems

Advanced Science, EarlyView.
A comprehensive understanding of the interactions between proteins, lipids and glycocalyx components at the immune synapse is still lacking. Here, an artificial and a semi‐artificial model contact system were established to reconstitute the cell‐cell contact in 3D. The model systems enable the examination of macromolecule enrichment or depletion at the
Franziska Ragaller, Amelie Maribel Schneider, Ellen Sjule, Renhua Sun, Xiao Han, Luca Andronico, Edward Jenkins, Michael Dustin, Adnane Achour, Erdinc Sezgin   +9 more
wiley   +1 more source

Nanoscale Covalent Organic Framework Confinement Enables Ultratough and Hyperelastic Hydrogels Applied as High‐Performance Electrolytes

Advanced Science, EarlyView.
Confinement by nanoscale covalent organic frameworks reinforces hydrogels, imparting exceptional mechanical strength and ionic conductivity for high‐performance electrolyte applications. ABSTRACT Hydrogels are widely applied in various fields, including energy storage and flexible electronics. However, their mechanical properties often fail to meet the
Peiyao Yan, Wei Zhao, Hao Wang, Lu Wu, Yedong Ma, Binting Huang, Hantao Xu, Xueyan Liu, Siqi Liu, Xinyu Dong, Xiaoyang Zhang, Wei Zhai, Weiwei Zhang, Lin Xu, Dan Zhao, Chaobin He   +15 more
wiley   +1 more source

ALKBH3 m1A Demethylase Deficiency Reduces Alzheimer's Amyloid‐β Pathology

Advanced Science, EarlyView.
This study identifies that ALKBH3‐driven m1A demethylation orchestrates Alzheimer's disease progression by disrupting mitochondrial and synaptic homeostasis. This epitranscriptomic mechanism suppresses PINK1‐mediated mitophagy via m1A erasure, leading to mitochondrial dysfunction, oxidative stress, elevated Aβ production, and impaired microglial ...
Yueyang Li, Sifei Yu, Kaidong Lu, Yujie Zhang, Mingjie Dong, Yan Peng, Liang Xue, Waleed Alam, Yuxuan Shui, Yi Zhou, Wuyunhan Ma, Meng Bao, Peiming Li, Peiyi Luo, Tiezhan Lu, Jiajia Li, Kang Zhang, Yuying Wang, Shuchen Yang, Nuoya Yin, Francesco Faiola, Zilong Gao, Jingfeng Zhou, Fei Zhao, Yali He, Magdalena J. Koziol   +25 more
wiley   +1 more source

Designing an Eddy Current Brake for Engine Testing

KnE Engineering, 2020
An Eddy Current Brake (ECB) has several advantages making it suitable for using in a dynamometer for testing engines. In this paper, a model is presented which considers the electromagnet’s core saturation to predict the performance of an ECB. A design is then proposed for a dual coil, single rotor ECB that meets the design requirement to dissipate a ...
Alexandre José Rosa Nunes, Francisco Miguel Ribeiro Proença Brojo   +1 more
openaire   +2 more sources

SAA/FPR2 Signaling Between Pericentral Hepatocytes and Macrophages Exacerbates Zonated Liver Transplant Injury

Advanced Science, EarlyView.
After liver transplantation, ischemia‐reperfusion injury is more severe in pericentral regions. Multiomic analyses of human grafts and mouse models identify FOXO1 activation in pericentral hepatocytes as an upstream driver of SAA secretion. SAA recruits and activates FPR2+ macrophages, amplifying local inflammation. Amilo‐5MER inhibits SAA bioactivity,
Feng Zhang, Rong Li, Tingting Wang, Jianhao Zhang, Zhengqi Wu, Qiang You, Xuying Liu, Cuicui Xiao, Jiebin Zhang, Haitian Chen, Jiaqi Xiao, Jia Yao, Jun Zheng, Yingcai Zhang, Hua Li, Shuhong Yi, Yang Yang, Qi Zhang, Xiaofeng Yuan, Yasong Liu   +19 more
wiley   +1 more source

S100A14 in Tumor‐Derived EVs Targets PIAS3 to Reprogram Astrocytes and Induce Immunosuppressive Microenvironment Promoting Brain Metastasis and Germacrone Reversal Effect

Advanced Science, EarlyView.
This study identifies S100A14 in tumor‐derived exosomes as a key driver of brain metastasis. S100A14 targets PIAS3 in astrocytes, activating STAT3 signaling and promoting immunosuppressive MDSCs recruitment via chemokine secretion. Germacrone, a natural compound, binds S100A14 to disrupt this axis, effectively inhibiting brain metastasis with low ...
Qian Feng, Xia Yang, Lin An, Xue‐Yu Wang, Ming‐Rui Wang, Zhuo‐Hong Cai, Cai‐Jun Xie, Li‐Jun Qiao, You‐Bi Shen, Xi‐Min Liang, Rong Zhang, Cai‐Yan Wang, Zhong‐Qiu Liu, Rong‐Rong Zhang   +13 more
wiley   +1 more source

Metal–Organic Frameworks as Micromotors with Tunable Engines and Brakes

Journal of the American Chemical Society, 2017
Herein, we report that UiO-type (UiO = University of Oslo) metal-organic frameworks (MOFs) can be transformed into self-propelled micromotors by employing several different metal-based propulsion systems. Incorporation of a bipyridine ligand into the UiO-67 lattice transforms the crystallites, upon metalation, into single-site, metal-based catalytic ...
Jinxing Li, Xiao Yu, Mingli Xu, Wenjuan Liu, Elodie Sandraz, Hsin Lan, Joseph Wang, Seth M. Cohen   +7 more
openaire   +2 more sources

A Nanobody‐LNP Platform for Targeting and Relicensing Dendritic Cells for Potent Cancer Immunotherapy

Advanced Science, EarlyView.
Plastin‐2 (PLS2) is identified as a dual‐function receptor on DCs that mediates both nanoparticle uptake and immunomodulation. A nanobody‐LNP platform is engineered to integrate antigen delivery with relicensing DCs. The therapeutic strategy elicits potent anti‐tumor T cell responses and leads to significant inhibition of established tumors in vivo ...
Shugang Qin, Zhiying Huang, Hai Huang, Yupei Zhang, Yuting Chen, Xi He, Zhenyi Niu, Zhongzheng Xiang, Chaoyu Zou, Xiangrong Song   +9 more
wiley   +1 more source