Results 51 to 60 of about 1,539,014 (284)

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Corn plants as temporary acoustic barrier to limit the effects of noise pollution

, 2021
Corn is a cereal imported into Europe from the Americas. It is used for human and animal feed, but there are also industrial uses such as the production of ethanol, of fuel for heating homes, or the production of starch. Corn grows in the summer in areas
Ciaburro G., Iannace G., Puyana-Romero V.   +2 more
core   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Acoustic liner optimisation and noise propagation through turbofan engine intake ducts

, 2013
The research in this thesis explores the prediction of fan noise propagation through turbofan engine intakes and its radiation to the far-field. The performance of acoustic liners installed in intakes to attenuate noise is the focus of the study.
Kewin, Matthew Fergus
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Investigation on Major Noise Sources of Vehicle Diesel Engine Based on Sound Intensity Measurement

Journal of Measurement Science and Instrumentation, 2011
In order to reduce the noise and vibration of the diesel engine,it is crucial to exactly identify the engine noise source character.Based on "two-microphone" method,the sound intensity measurement of a vehicle four-stroke diesel engine was carried out in
Bao-cheng ZHANG, Peng LI, Xiao-xiao DENG, Fu-qiang ZHANG   +3 more
doaj  

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Acoustic measurements for the combustion diagnosis of diesel engines fuelled with biodiesels [PDF]

, 2013
In this paper, an experimental investigation was carried out on the combustion process of a compression ignition (CI) engine running with biodiesel blends under steady state operating conditions.
Gu, Fengshou, Ball, Andrew, Zhen, Dong, Wang, Tie, Tesfa, Belachew   +4 more
core   +1 more source

Vibration Analysis of the Engine Using Biofuel Blends: A Review

MATEC Web of Conferences, 2018
The vibrations and noise of the internal combustion engine may be affected by several factors such as combustion pressure, movement of the piston-crank mechanism, coolant factor flow, engine body, and fuel inlet of the injector.
Erdiwansyah, Sani M.SM., Mamat Rizalman., Khoerunnisa Fitri, Rajkumar AR, Razak N.F.D, Sardjono R.E   +6 more
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source