Results 181 to 190 of about 528,436 (209)

Porcine Deltacoronavirus M Protein Binds NLRP3 to Promote Inflammasome Assembly via Competition with TRIM31

Advanced Science, EarlyView.
Porcine deltacoronavirus (PDCoV) infection induces severe intestinal inflammation and acute diarrhea in piglets, yet the molecular mechanism remains incompletely understood. The M protein activates NLRP3 inflammasome through dual mechanisms: direct binding to the NLRP3 LRR domain and disruption of TRIM31‐mediated K48‐linked ubiquitination.
Jinhui Hou, Fangfang Han, Anqi Liu, Yang Yu, Rui Zhao, Zhengting Shi, Yanrong Lv, Jinli Liu, Shaopo Zu, Zhanyong Wei, Jin Yuan, Hui Hu   +11 more
wiley   +1 more source

ReVesicle: Curation and Equilibration of Lipid Vesicles for Mesoscale Simulations. [PDF]

J Chem Theory Comput
Castelli M, Casalino L, Amaro RE.
europepmc   +1 more source

An Immediate‐Response Detection System for γ‐Hydroxybutyrate to Enhance Personal Safety in Social Environments

Advanced Science, EarlyView.
A graphene‐based electrical biosensor enables rapid and highly sensitive detection of GHB at 100 fm in both standard solutions and artificial urine, providing reliable point‐of‐need screening for drug‐facilitated sexual assault. The platform demonstrates strong selectivity, fast response, and a wide dynamic range, supporting accurate detection in ...
Jai Eun An, Jisung Kwak, Kyung Ho Kim, Chaeeun Kim, Sung Eun Seo, Nathaniel S. Hwang, Yong‐Sang Ryu, Hyun Seok Song, Oh Seok Kwon   +8 more
wiley   +1 more source

apoCHARMM: High-performance molecular dynamics simulations on GPUs for advanced simulation methods. [PDF]

J Chem Phys
Prasad S, Aviat F, Gonzales JE, Brooks BR.   +3 more
europepmc   +1 more source

Development of a Fully Autonomous Offline Assistive System for Visually Impaired Individuals: A Privacy-First Approach. [PDF]

Sensors (Basel)
Mekonnen FY, Al Bataineh MF, Abu Abdoun D, Serag A, Tamiru KT, Abula W, Darota S.   +6 more
europepmc   +1 more source

Kinetic Compatibility as a Predictor of PTP1B Inhibitor Combination Outcomes: An Integrated Experimental and Computational Study. [PDF]

ChemMedChem
Trapala J, Álvarez-Añorve LI, Vasquez-Martínez N, Chavira-Suárez E, Vásquez-Bochm L, Matuz-Mares D, Cortés-Benítez F, González-Andrade M.   +7 more
europepmc   +1 more source

Origins of Reactivity in SAM-Utilizing Ribozyme SAMURI-Catalyzed RNA Alkylation. [PDF]

J Am Chem Soc
Puyo-Fourtine J, Du Y, McCarthy E, Ekesan Ş, York DM.   +4 more
europepmc   +1 more source

Prion Protein-Derived Cell-Penetrating Peptide Inhibits Type II Diabetes-Associated Islet Amyloid Polypeptide Aggregation and Cytotoxicity. [PDF]

Biochemistry
Oh Y, Palanikumar L, Howarth M, Maity D, Ali L, Mustafa M, Kumar S, Hamilton AD, Magzoub M.   +8 more
europepmc   +1 more source

Engineered strains as living factories: efficient biosynthesis and modification of natural products via synthetic biology and one-pot chemical tandem reactions. [PDF]

Front Microbiol
Liu S, Chen P, Li H, Dong W, Xu Q.
europepmc   +1 more source

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P-SHAKE: A quadratically convergent SHAKE in

Journal of Computational Physics, 2007
Pedro Gonnet
exaly