Results 11 to 20 of about 15,097,055 (209)

A grid computing framework for commercial simulation packages [PDF]

open access: yes, 2007
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.An increased need for collaborative research among different organizations, together with continuing advances in communication technology and computer ...
Mustafee, Navonil
core   +7 more sources

Future trends in railway engineering [PDF]

open access: yes, 2009
This article reviews the current state of railway engineering with a focus on the steady development of conventional technology that has led to the 575 km/h run of the French TGV train in 2007.
Iwnicki, Simon D., Iwnicki, S.
core   +1 more source

Cloud computing and context-awareness: A study of the adapted user experience [PDF]

open access: yes, 2012
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Today, mobile technology is part of everyday life and activities and the mobile ecosystems are blossoming, with smartphones and tablets being the major ...
Grønli, Tor-Morten
core   +7 more sources

A Situational Assessment of the Diagnostic Landscape and Organizational Readiness to Implement Next‐Generation Sequencing at Two Childhood Cancer Treatment Centers in Ghana

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Next‐generation sequencing (NGS) has emerged as a promising approach to improve diagnostic accuracy, but its feasibility in low‐ and middle‐income countries remains unknown. This study characterized the diagnostic landscape and assessed organizational readiness for NGS implementation at two childhood cancer treatment centers in Accra ...
Melissa Carvalho   +6 more
wiley   +1 more source

Web of Science - Engineering, Computing & Technology Journals Dataset

open access: yes, 2022
This dataset contains information about journals in the field of Engineering, Computing & Technology available on the web of science. Currently, there are 1656 journals in this field.The property are as follows:- Paper- Publisher- ISSN / eISSN- Web ...
Deniz, A (via Mendeley Data)
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Analysis of Engineering and Engineering Technology Student Strength Patterns Using StrengthsFinder [PDF]

open access: yes, 2020
Strengths as measured by Gallup’s Clifton StrengthsFinder test have been shown to play a role in workplace success around the world in industry and academia.
Freeman, Steven   +2 more
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

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