Results 71 to 80 of about 11,998,035 (258)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

INDUSTRIAL ENGINEERING TECHNIQUES AND TOOLKIT ON BASIS OF COMMUNICATION PROCESS SCHEDULING

open access: yesВестник Донского государственного технического университета, 2018
Industrial engineering techniques are total operations and methods for the production or rendering services. The selection of the method and industrial engineering techniques — job shop-type, batch or repetitive — is primarily subject to the industrial ...
Tatyana V. Simonyan   +1 more
doaj  

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

BIOPROCESS SYSTEMS ENGINEERING: TRANSFERRING TRADITIONAL PROCESS ENGINEERING PRINCIPLES TO INDUSTRIAL BIOTECHNOLOGY

open access: yesComputational and Structural Biotechnology Journal, 2012
The complexity of the regulatory network and the interactions that occur in the intracellular environment of microorganisms highlight the importance in developing tractable mechanistic models of cellular functions and systematic approaches for modelling ...
Michalis Koutinas   +3 more
doaj   +3 more sources

INDUSTRIAL ENGINEERING TECHNIQUES AND TOOLKIT ON BASIS OF COMMUNICATION PROCESS SCHEDULING

open access: yesAdvanced Engineering Research, 2011
Industrial engineering techniques are total operations and methods for the production or rendering services. The selection of the method and industrial engineering techniques — job shop-type, batch or repetitive — is primarily subject to the industrial ...
Tatyana V. Simonyan   +1 more
doaj  

Accounting engineering for sustainable development

open access: yesSHS Web of Conferences, 2017
The article deals with the sustainable development of industrial enterprises in Russia, accounting for sustainable industrial growth of the national economy, tools of accounting engineering aimed at creating an information basis of transformation the ...
Sidornya A.
doaj   +1 more source

Discovery, Characterisation, Engineering and Applications of Ene Reductases for Industrial Biocatalysis

open access: yesACS Catalysis, 2018
Recent studies of multiple enzyme families collectively referred to as ene-reductases (ERs) have highlighted potential industrial application of these biocatalysts in the production of fine and speciality chemicals.
H. Toogood, N. Scrutton
semanticscholar   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Identification and analysis of research trends in industrial engineering in the papers published between January 2012 to January 2015

open access: yesآموزش مهندسی ایران, 2015
In the recent decades, amount of researches in the field of industrial engineering grew increasingly which makes hard to find a new area in this field. Indeed it needs extensive searches on the many published papers related to the field.
Abdullah Aghaei, Mojtaba Hajian Heydari
doaj   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

open access: yesFEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli   +3 more
wiley   +1 more source

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