Results 51 to 60 of about 499,978 (263)

Bioprocess systems engineering: transferring traditional process engineering principles to industrial biotechnology

Computational and Structural Biotechnology Journal, 2012
The complexity of the regulatory network and the interactions that occur in the intracellular environment of microorganisms highlight the importance in developing tractable mechanistic models of cellular functions and systematic approaches for modelling ...
Michalis Koutinas, Alexandros Kiparissides, Efstratios N Pistikopoulos, Athanasios Mantalaris   +3 more
doaj   +3 more sources

INDUSTRIAL ENGINEERING TECHNIQUES AND TOOLKIT ON BASIS OF COMMUNICATION PROCESS SCHEDULING

Вестник Донского государственного технического университета, 2018
Industrial engineering techniques are total operations and methods for the production or rendering services. The selection of the method and industrial engineering techniques — job shop-type, batch or repetitive — is primarily subject to the industrial ...
Tatyana V. Simonyan, Dmitry B. Dashchinskiy   +1 more
doaj  

Identification and analysis of research trends in industrial engineering in the papers published between January 2012 to January 2015

آموزش مهندسی ایران, 2015
In the recent decades, amount of researches in the field of industrial engineering grew increasingly which makes hard to find a new area in this field. Indeed it needs extensive searches on the many published papers related to the field.
Abdullah Aghaei, Mojtaba Hajian Heydari
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

INDUSTRIAL ENGINEERING TECHNIQUES AND TOOLKIT ON BASIS OF COMMUNICATION PROCESS SCHEDULING

Advanced Engineering Research, 2011
Industrial engineering techniques are total operations and methods for the production or rendering services. The selection of the method and industrial engineering techniques — job shop-type, batch or repetitive — is primarily subject to the industrial ...
Tatyana V. Simonyan, Dmitry B. Dashchinskiy   +1 more
doaj  

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Tools of integration of innovation-oriented machine-building enterprises in industrial park environment

Vìsnik Žitomirsʹkogo Deržavnogo Tehnologìčnogo Unìversitetu: Ekonomìčnì Nauki, 2017
The research is devoted to the development of the tools for the integration of innovation-oriented mechanical engineering enterprises into the environment of industrial park as functional economic systems, which are capable on the own development basis ...
К.О. Boiarynova
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source